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使用异丙醇垫进行血液乙醇采样不会导致假阳性结果。

Isopropyl alcohol pad use for blood ethanol sampling does not cause false-positive results.

作者信息

Miller Michael A, Rosin Alex, Levsky Marc E, Gregory Timothy J D, Crystal Chad S

机构信息

Department of Emergency Medicine, Darnall Army Medical Center, Ft. Hood, Texas 76544, USA.

出版信息

J Emerg Med. 2007 Jul;33(1):9-10. doi: 10.1016/j.jemermed.2006.10.005. Epub 2007 May 30.

DOI:10.1016/j.jemermed.2006.10.005
PMID:17630067
Abstract

This was a retrospective analysis of prospective data collected from a study of blood ethanol levels after the use of the alcohol-based hand sanitizer (ABHS). A total of 5 male volunteers were enrolled. Eight of the 10 total blood ethanol level measurements were drawn after skin preparation with Kendall WEBCOL Alcohol Preps (APP) containing 70% isopropyl alcohol. All had an initial and post-ABHS application blood alcohol level (BAL) drawn, for a total of 10 BAL measurements. Measurements upon completion of the study were <5 mg/dL in all 5 study participants and in each of the 10 blood draws regardless of skin preparation technique. This study demonstrates that the use of isopropyl skin prep pads is unlikely to cause significant false-positive blood ethanol levels.

摘要

这是一项对前瞻性数据的回顾性分析,这些数据来自一项关于使用含酒精洗手液(ABHS)后血液乙醇水平的研究。总共招募了5名男性志愿者。在使用含有70%异丙醇的肯德尔WEBCOL酒精擦拭巾(APP)进行皮肤准备后,进行了10次血液乙醇水平测量中的8次。所有志愿者均采集了使用ABHS前和使用后的血液酒精水平(BAL),共进行了10次BAL测量。无论采用何种皮肤准备技术,在所有5名研究参与者以及10次采血中的每一次中,研究完成时的测量结果均<5mg/dL。这项研究表明,使用异丙醇皮肤准备垫不太可能导致血液乙醇水平出现显著的假阳性。

相似文献

1
Isopropyl alcohol pad use for blood ethanol sampling does not cause false-positive results.使用异丙醇垫进行血液乙醇采样不会导致假阳性结果。
J Emerg Med. 2007 Jul;33(1):9-10. doi: 10.1016/j.jemermed.2006.10.005. Epub 2007 May 30.
2
Does the clinical use of ethanol-based hand sanitizer elevate blood alcohol levels? A prospective study.使用含乙醇的洗手液进行临床手部消毒会提高血液酒精含量吗?一项前瞻性研究。
Am J Emerg Med. 2006 Nov;24(7):815-7. doi: 10.1016/j.ajem.2006.05.006.
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Isopropyl alcohol skin prep pads: the extreme case.异丙醇皮肤预擦垫:极端案例。
J Emerg Med. 2007 Oct;33(3):289. doi: 10.1016/j.jemermed.2007.02.063. Epub 2007 Jul 20.
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Can alcohol-based hand-rub solutions cause you to lose your driver's license? Comparative cutaneous absorption of various alcohols.含酒精的洗手液会导致你失去驾照吗?各种酒精的皮肤吸收比较。
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Skin disinfection methods: prospective evaluation and postimplementation results.皮肤消毒方法:前瞻性评估和实施后的结果。
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Lack of effect on blood alcohol level of swabbing venepuncture sites with 70% isopropyl alcohol.用 70%异丙醇擦拭静脉穿刺部位对血液酒精水平没有影响。
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Alcohol-based hand sanitizer: can frequent use cause an elevated blood alcohol level?含酒精洗手液:频繁使用会导致血液酒精水平升高吗?
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引用本文的文献

1
Does cleaning of venipuncture site with alcohol affect blood ethanol concentration?用酒精清洁静脉穿刺部位会影响血液乙醇浓度吗?
Heliyon. 2024 May 17;10(10):e31517. doi: 10.1016/j.heliyon.2024.e31517. eCollection 2024 May 30.
2
To disinfect or not to disinfect that is the question - Procedure when drawing blood for alcohol measurements in Denmark.消毒还是不消毒,这是个问题——丹麦血液酒精含量检测采血程序
Pract Lab Med. 2024 Feb 28;39:e00381. doi: 10.1016/j.plabm.2024.e00381. eCollection 2024 Mar.
3
Blood alcohol concentration in the clinical laboratory: a narrative review of the preanalytical phase in diagnostic and forensic testing.
临床实验室中的血液酒精浓度:诊断和法医检测中分析前阶段的叙述性综述。
Biochem Med (Zagreb). 2024 Feb 15;34(1):010501. doi: 10.11613/BM.2024.010501. Epub 2023 Dec 15.
4
The alcohol used for cleansing the venipuncture site does not jeopardize blood and plasma alcohol measurement with head-space gas chromatography and an enzymatic assay.用于清洁静脉穿刺部位的酒精不会影响采用顶空气相色谱法和酶法测定血液和血浆中的酒精含量。
Biochem Med (Zagreb). 2017 Jun 15;27(2):398-403. doi: 10.11613/BM.2017.041.