溶血性贫血导致的碳氧血红蛋白升高。

Carboxyhemoglobin elevation due to hemolytic anemia.

作者信息

Hampson Neil B

机构信息

Center for Hyperbaric Medicine, Virginia Mason Medical Center, Seattle, Washington, USA.

出版信息

J Emerg Med. 2007 Jul;33(1):17-9. doi: 10.1016/j.jemermed.2006.10.004. Epub 2007 May 30.

DOI:10.1016/j.jemermed.2006.10.004

PMID:17630069

Abstract

A critically ill man with drug-induced hemolytic anemia and hepatic failure was hospitalized at a private academic medical center in Seattle, Washington. Intravascular hemolysis with associated endogenous carbon monoxide (CO) production resulted in elevation of the patient's carboxyhemoglobin (COHb) level to as high as 9.7%. Serial measurements of the patient's COHb level were obtained and compared with other conventional measures of hemolytic activity. With the availability of new non-invasive measurement technology to detect COHb elevations, emergency clinicians are likely to see COHb elevation as a manifestation of hemolytic anemia.

摘要

一名患有药物性溶血性贫血和肝功能衰竭的重症男子在华盛顿州西雅图的一家私立学术医疗中心住院。血管内溶血伴有内源性一氧化碳（CO）生成，导致患者的碳氧血红蛋白（COHb）水平升高至9.7%。对患者的COHb水平进行了连续测量，并与其他传统的溶血活性指标进行了比较。随着检测COHb升高的新型非侵入性测量技术的出现，急诊临床医生可能会将COHb升高视为溶血性贫血的一种表现。