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体外膜肺氧合相关溶血中内源性一氧化碳的产生:即时检测一氧化碳血氧饱和度仪测定碳氧血红蛋白在检测溶血方面的潜在应用。

Endogenous carbon monoxide production in extracorporeal membrane oxygenation-related hemolysis: potential use of point-of-care CO-oximetry carboxyhemoglobin to detect hemolysis.

作者信息

Kai Man Chan, Koon Ngai Lam

机构信息

Department of Anaesthesia and Intensive Care Prince of Wales Hospital Chinese University of Hong Kong Shatin Hong Kong.

Department of Intensive Care North District Hospital Chinese University of Hong Kong Sheung Shui Hong Kong.

出版信息

Clin Case Rep. 2018 Jan 3;6(2):346-349. doi: 10.1002/ccr3.1351. eCollection 2018 Feb.

DOI:10.1002/ccr3.1351
PMID:29445475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5799617/
Abstract

Extracorporeal membrane oxygenation (ECMO)-related hemolysis is a rare but devastating condition. Death is inevitable without early recognition and prompt management. Endogenous carbon monoxide production, as an epiphenomenon of hemolysis, potentially allows rapid detection of such condition by use of point-of-care CO-oximetry carboxyhemoglobin.

摘要

体外膜肺氧合(ECMO)相关的溶血是一种罕见但极具破坏性的病症。若不及早识别并迅速处理,死亡将不可避免。内源性一氧化碳生成作为溶血的一种附带现象,有可能通过使用即时护理一氧化碳血氧测定法检测碳氧血红蛋白来快速检测出这种病症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8903/5799617/756692051630/CCR3-6-346-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8903/5799617/20bb4be4a5fd/CCR3-6-346-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8903/5799617/756692051630/CCR3-6-346-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8903/5799617/20bb4be4a5fd/CCR3-6-346-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8903/5799617/756692051630/CCR3-6-346-g002.jpg

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本文引用的文献

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Carboxyhemoglobin levels in medical intensive care patients: a retrospective, observational study.医疗重症监护病房患者的碳氧血红蛋白水平:一项回顾性观察研究。
Crit Care. 2012 Jan 11;16(1):R6. doi: 10.1186/cc11138.
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羧基血红蛋白(CO-Hb)与体外膜肺氧合中的溶血及医院死亡率的相关性:一项回顾性注册研究
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Crit Care. 2021 Apr 27;25(1):159. doi: 10.1186/s13054-021-03582-w.
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