Suh Jun-Gyo, Choi Woo Suk, Paick Jae-Seung, Kim Soo Woong
Department of Urology, Seoul National University Hospital, Seoul, Korea.
Korean J Urol. 2013 Jul;54(7):442-7. doi: 10.4111/kju.2013.54.7.442. Epub 2013 Jul 15.
Although direct-vision internal urethrotomy can be performed for the management of short, bulbar urethral strictures, excision and end-to-end anastomosis remains the best procedure to guarantee a high success rate. We performed a retrospective evaluation of patients who underwent bulbar end-to-end anastomosis to assess the factors affecting surgical outcome.
We reviewed 33 patients with an average age of 55 years who underwent bulbar end-to-end anastomosis. Stricture etiology was blunt perineal trauma (54.6%), iatrogenic (24.2%), idiopathic (12.1%), and infection (9.1%). A total of 21 patients (63.6%) underwent urethrotomy, dilation, or multiple treatments before referral to our center. Clinical outcome was considered a treatment failure when any postoperative instrumentation was needed.
Mean operation time was 151 minutes (range, 100 to 215 minutes) and mean excised stricture length was 1.5 cm (range, 0.8 to 2.3 cm). At a mean follow-up of 42.6 months (range, 8 to 96 months), 29 patients (87.9%) were symptom-free and required no further procedure. Strictures recurred in 4 patients (12.1%) within 5 months after surgery. Of four recurrences, one patient was managed successfully by urethrotomy, whereas the remaining three did not respond to urethrotomy or dilation and required additional urethroplasty. The recurrence rate was significantly higher in the patients with nontraumatic causes (iatrogenic in three, infection in one patient) than in the patients with traumatic etiology.
Excision and end-to-end anastomosis for short, bulbar urethral stricture has an acceptable success rate of 87.9%. However, careful consideration is needed to decide on the surgical procedure if the stricture etiology is nontraumatic.
尽管直视下尿道内切开术可用于治疗短段球部尿道狭窄,但切除并端端吻合术仍是确保高成功率的最佳手术方式。我们对接受球部端端吻合术的患者进行了回顾性评估,以分析影响手术结果的因素。
我们回顾了33例平均年龄55岁、接受球部端端吻合术的患者。狭窄病因包括会阴部钝性创伤(54.6%)、医源性(24.2%)、特发性(12.1%)和感染(9.1%)。共有21例患者(63.6%)在转诊至我们中心之前接受了尿道切开术、扩张术或多次治疗。若术后需要任何器械操作,则临床结果视为治疗失败。
平均手术时间为151分钟(范围100至215分钟),平均切除狭窄长度为1.5厘米(范围0.8至2.3厘米)。平均随访42.6个月(范围8至96个月)时,29例患者(87.9%)无症状且无需进一步手术。4例患者(12.1%)在术后5个月内出现狭窄复发。在4例复发患者中,1例患者通过尿道切开术成功治疗,而其余3例对尿道切开术或扩张术无反应,需要再次行尿道成形术。非创伤性病因患者(3例医源性、1例感染)的复发率显著高于创伤性病因患者。
短段球部尿道狭窄切除并端端吻合术的成功率为87.9%,可接受。然而,如果狭窄病因是非创伤性的,则需要仔细考虑决定手术方式。