Mandal Pijus K, McMurray John S
Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas 77030, USA.
J Org Chem. 2007 Aug 17;72(17):6599-601. doi: 10.1021/jo0706123. Epub 2007 Jul 14.
In situ generation of molecular hydrogen by addition of triethylsilane to palladium-charcoal catalyst results in rapid and efficient reduction of multiple bonds, azides, imines, and nitro groups, as well as benzyl group and allyl group deprotection under mild, neutral conditions.
通过向钯炭催化剂中加入三乙基硅烷原位生成分子氢，可在温和、中性条件下快速有效地还原多重键、叠氮化物、亚胺和硝基，以及进行苄基和烯丙基的脱保护反应。
