脚周核：深部脑刺激的新靶点？

The peripeduncular nucleus: a novel target for deep brain stimulation?

作者信息

Zrinzo Ludvic, Zrinzo Laurence V, Hariz Marwan

出版信息

Neuroreport. 2007 Aug 6;18(12):1301-2. doi: 10.1097/WNR.0b013e3282638603.

Abstract

The pedunculopontine nucleus, a promising new target for deep brain stimulation in Parkinson's disease, straddles the pontomesencephalic junction--unfamiliar territory to most functional neurosurgeons. This contribution reviews the anatomy of the pedunculopontine and peripeduncular nuclei. Given the reported findings of Mazzone et al. in NeuroReport, the authors postulate that the peripeduncular nucleus might be of previously unexpected clinical relevance.

摘要

脚桥核是帕金森病深部脑刺激一个很有前景的新靶点，它横跨脑桥中脑交界处，这对大多数功能神经外科医生来说是个陌生的区域。本文综述了脚桥核和脚周核的解剖结构。鉴于马佐内等人在《神经报告》上发表的研究结果，作者推测脚周核可能具有此前未被预料到的临床相关性。