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[弥漫性轴索损伤导致的长期创伤性昏迷]

[Prolonged traumatic coma caused by diffuse axonal lesions].

作者信息

Tominaga I, Matsuo Y, Kato Y, Onaya M, Kasahara M, Yuzuriha T, Oda T, Kashima H, Wasada K

机构信息

Service de Neuropsychiatrie, Hôpital National de Chiba, Japan.

出版信息

Rev Neurol (Paris). 1991;147(10):658-62.

PMID:1763255
Abstract

A 22-year old male patient was admitted for deep coma probably of traumatic origin. There was neither fracture of the skull nor expansive intracranial lesion. The patient survived for 6 years and 8 months without any change in consciousness. Post-mortem neuropathological examination showed lesions which predominated in the white matter and had features that were compatible with diffuse axonal injury. The mechanism responsible for these lesions seems to be stretching and shearing of axones at the moment of impact. The exceptionally long duration of survival probably accounts for the severity of the lesions observed.

摘要

一名22岁男性患者因可能由外伤引起的深度昏迷入院。既没有颅骨骨折,也没有颅内占位性病变。患者存活了6年零8个月,意识没有任何变化。尸检神经病理学检查显示病变主要位于白质,具有与弥漫性轴索损伤相符的特征。这些病变的发生机制似乎是撞击瞬间轴突的拉伸和剪切。存活时间异常之长可能是观察到病变严重程度的原因。

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