Gay C G, Zuerner R, Bannantine J P, Lillehoj H S, Zhu J J, Green R, Pastoret P P
United States Department of Agriculture, Agricultural Research Service, National Program Staff, Animal Production and Protection, Beltsville, MD, USA.
Rev Sci Tech. 2007 Apr;26(1):49-67.
The current explosion in new high-throughput technologies arising from microbial and animal genomics studies is enabling the analysis of the genome, transcriptome, and proteome and offers the opportunity to gain a better understanding of the molecular pathways underlying pathogen biology, the host immune system, and host-pathogen interactions. These new tools can be applied to veterinary pathogens to overcome some of the current hurdles in the discovery of highly effective vaccines for farmed livestock and poultry.
微生物和动物基因组学研究中涌现的新型高通量技术的迅猛发展，使得对基因组、转录组和蛋白质组的分析成为可能，并有机会更好地理解病原体生物学、宿主免疫系统以及宿主-病原体相互作用背后的分子途径。这些新工具可应用于兽医病原体研究，以克服目前在为养殖家畜和家禽研发高效疫苗过程中遇到的一些障碍。
