Ojha Shivani, Kostrzynska Magdalena
Agriculture and Agri-Food Canada, Food Research Program, 93 Stone Road West, Guelph, Ontario, N1G 5C9, Canada.
Vet Res. 2008 Jan-Feb;39(1):4. doi: 10.1051/vetres:2007042. Epub 2007 Oct 25.
The advancement in functional genomics, such as DNA microarrays along with the genome availability of important pathogens as well as of human and livestock species has allowed scientists to study the expression of thousands of genes in a single step. In the past decade, DNA arrays have been employed to study infectious processes of pathogens, in diagnostics, and to study host-pathogen interactions. The generation of enormous data sets by microarray experiments also stimulated the growth of a new generation of analytical software. The information provided by microarray experiments has been useful in generating new hypotheses for future research. The concept of DNA array technology has been utilized in the development of novel diagnostic methods. This review highlights the application of microarrays in the field of veterinary research.
功能基因组学的进展，如DNA微阵列技术，以及重要病原体、人类和家畜物种基因组的可得性，使科学家能够在一步中研究数千个基因的表达。在过去十年中，DNA阵列已被用于研究病原体的感染过程、诊断以及宿主-病原体相互作用。微阵列实验产生的大量数据集也刺激了新一代分析软件的发展。微阵列实验提供的信息有助于为未来研究提出新的假设。DNA阵列技术的概念已被用于开发新型诊断方法。本综述重点介绍了微阵列在兽医研究领域的应用。
