Stoss F, Meier-Ruge W
Chirurgische Abteilung, Krankenhaus Dornbirn, Austria.
Surg Endosc. 1991;5(3):146-9. doi: 10.1007/BF02653223.
Neuronal colonic dysplasia is a separate clinical entity belonging to the group of congenital defects of intestinal innervation. Its enzyme-histochemical diagnosis is possible by endoscopic biopsy examination of the rectosigmoid. Enzyme-histochemically, it is characterized by dysplasia of the submucous plexus secondary to developmental defects. The principal clinical feature is weak propulsive motility. A clinical study was carried out to investigate the role of neuronal colonic dysplasia in the aetiology and pathogenesis of primary chronic constipation and diverticulosis of the sigmoid colon in adults.
神经元性结肠发育异常是一种独立的临床实体，属于肠道神经支配先天性缺陷组。通过直肠乙状结肠的内镜活检检查可进行酶组织化学诊断。在酶组织化学方面，其特征是继发于发育缺陷的黏膜下神经丛发育异常。主要临床特征是推进性蠕动减弱。开展了一项临床研究，以调查神经元性结肠发育异常在成人原发性慢性便秘和乙状结肠憩室病的病因学和发病机制中的作用。
