Stoss F
Department of Surgery, Dornbirn Hospital, Austria.
Int J Colorectal Dis. 1990 May;5(2):106-12. doi: 10.1007/BF00298481.
Intestinal muscle and the autonomic nervous system constitute a neuromuscular unit. A clinical study was undertaken to seek neurogenic causes of impaired motility affecting the rectosigmoid junction and rectum. Patients with primary chronic constipation were shown by enzyme-histochemical examination of biopsies to have neuronal colonic dysplasia of the rectosigmoid, whereas the latter was normally innervated in healthy controls. The present investigations provide a fresh insight, underpinned by histological findings, into the aetiology of chronic constipation and make a contribution to its operative treatment.
肠道肌肉和自主神经系统构成一个神经肌肉单元。开展了一项临床研究，以寻找影响直肠乙状结肠交界处和直肠的运动功能受损的神经源性病因。通过对活检组织进行酶组织化学检查发现，原发性慢性便秘患者的直肠乙状结肠存在神经元性结肠发育异常，而在健康对照者中，该部位神经支配正常。本研究基于组织学发现，为慢性便秘的病因提供了新的见解，并为其手术治疗做出了贡献。
