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[荧光细胞学。尿细胞学的改进]

[Fluorescence cytology. Improvement of urinary cytology].

作者信息

Tritschler S, Tauber S, Meier R, Stepp H, Karl A, Zaak D, Stief C G

机构信息

Urologische Klinik und Poliklink, Klinikum Grosshadern, Ludwig-Maximilians-Universität, Marchioninistrasse 15, 81377 München.

出版信息

Urologe A. 2007 Sep;46(9):1121-3. doi: 10.1007/s00120-007-1449-8.

Abstract

Urothelial cancer of the bladder is a frequent disease, and urinary cytology often is used as a routine diagnostic tool. But this technique has an impaired sensitivity in low-grade tumours, and as a subjective method it is highly dependent on the experience of the cytologist. Here we present the technique of fluorescence cytology as an improvement of conventional cytology. This method is potentially able to compensate for the disadvantages of urinary cytology as it is an automated process that uses the principles of 5-Ala-induced photodynamic diagnosis (PDD).

摘要

膀胱尿路上皮癌是一种常见疾病,尿液细胞学检查常被用作常规诊断工具。但该技术在低级别肿瘤中的敏感性受损,并且作为一种主观方法,它高度依赖于细胞病理学家的经验。在此,我们介绍荧光细胞学技术,作为对传统细胞学的一种改进。这种方法有可能弥补尿液细胞学的缺点,因为它是一个利用5-氨基乙酰丙酸诱导的光动力诊断(PDD)原理的自动化过程。

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