Lane Síle, Rippon Helen J, Bishop Anne E
Stem Cells and Regenerative Medicine, Section on Experimental Medicine and Toxicology, Imperial College, Faculty of Medicine, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
Regen Med. 2007 Jul;2(4):407-15. doi: 10.2217/17460751.2.4.407.
Repair or regeneration of defective lung tissue would be of great clinical use. Potential cellular sources for the regeneration of lung tissue in vivo or lung tissue engineering in vitro include endogenous pulmonary stem cells, extrapulmonary circulating stem cells and embryonic stem cells. This review summarizes the recent research on each of these stem cell types and their potential for use in the treatment of lung injury and disease.
修复或再生有缺陷的肺组织将具有重大临床应用价值。体内肺组织再生或体外肺组织工程的潜在细胞来源包括内源性肺干细胞、肺外循环干细胞和胚胎干细胞。本文综述了近年来对这些干细胞类型的研究及其在治疗肺损伤和疾病中的应用潜力。