Handa U, Nanda A, Mohan H
Department of Pathology, Government Medical College & Hospital, Sector 32A, Chandigarh, India.
Cytopathology. 2007 Aug;18(4):250-4. doi: 10.1111/j.1365-2303.2006.00356.x.
Renal angiomyolipoma is an uncommon benign tumour composed of smooth muscle cells, blood vessels and adipose tissue. The cytological findings of this tumour are described.
A retrospective analysis of four cases of angiomyolipoma diagnosed on fine-needle aspiration cytology (FNAC) during the period 1998-2004 was carried out. All the aspirations were carried out under ultrasonographic image guidance.
Smears from three cases showed oval- to spindle-shaped tumour cells, cohesive stromal fragments embedded in adipose tissue and branching blood vessels in a haemorrhagic background. No mitotic figures were seen. Smears from one case showed adipose tissue and blood. In this case, sections from the cell block showed mature adipose tissue and small blood vessels.
The diagnosis of angiomyolipoma can be made by FNAC under image guidance and a cell block may be quite helpful in making a correct diagnosis. It is important to establish a correct preoperative diagnosis as treatment of these tumours is conservative and this obviates the need for total nephrectomy.
肾血管平滑肌脂肪瘤是一种由平滑肌细胞、血管和脂肪组织组成的罕见良性肿瘤。本文描述了该肿瘤的细胞学表现。
对1998年至2004年间经细针穿刺细胞学检查（FNAC）诊断为血管平滑肌脂肪瘤的4例病例进行回顾性分析。所有穿刺均在超声图像引导下进行。
3例涂片显示为椭圆形至梭形肿瘤细胞、嵌入脂肪组织的粘性基质碎片以及出血背景下的分支血管。未见有丝分裂象。1例涂片显示为脂肪组织和血液。在该病例中，细胞块切片显示为成熟脂肪组织和小血管。
在图像引导下通过FNAC可诊断血管平滑肌脂肪瘤，细胞块对做出正确诊断可能很有帮助。术前建立正确诊断很重要，因为这些肿瘤的治疗是保守的，这避免了全肾切除术的必要性。
