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药剂师干预在心血管疾病管理中的有效性。

Effectiveness of pharmacist's intervention in the management of cardiovascular diseases.

作者信息

Omboni Stefano, Caserini Marina

机构信息

Department of Clinical Research Unit, Italian Institute of Telemedicine, Solbiate Arno, Italy.

出版信息

Open Heart. 2018 Jan 3;5(1):e000687. doi: 10.1136/openhrt-2017-000687. eCollection 2018.

Abstract

The pharmacist may play a relevant role in primary and secondary prevention of cardiovascular diseases, mainly through patient education and counselling, drug safety management, medication review, monitoring and reconciliation, detection and control of specific cardiovascular risk factors (eg, blood pressure, blood glucose, serum lipids) and clinical outcomes. Systematic reviews of randomised controlled and observational studies have documented an improved control of hypertension, dyslipidaemia or diabetes, smoking cessation and reduced hospitalisation in patients with heart failure, following a pharmacist's intervention. Limited proof for effectiveness is available for humanistic (patient satisfaction, adherence and knowledge) and economic outcomes. A multidisciplinary approach, including medical input plus a pharmacist, specialist nurse or both, and a greater involvement of community rather than hospital pharmacists, seems to represent the most efficient and modern healthcare delivery model. However, further well-designed research is demanded in order to quantitatively and qualitatively evaluate the impact of pharmacist's interventions on cardiovascular disease and to identify specific areas of impact of collaborative practice. Such research should particularly focus on the demonstration of a sensitivity to community pharmacist's intervention. Since pharmacy services are easily accessible and widely distributed in the community setting, a maximum benefit should be expected from interventions provided in this context.

摘要

药剂师在心血管疾病的一级和二级预防中可能发挥重要作用,主要通过患者教育与咨询、药物安全管理、用药评估、监测与核对、特定心血管危险因素(如血压、血糖、血脂)的检测与控制以及临床结局管理来实现。对随机对照研究和观察性研究的系统评价表明,在药剂师进行干预后,高血压、血脂异常或糖尿病患者的病情得到了更好的控制,吸烟得以戒断,心力衰竭患者的住院率也有所降低。关于人文(患者满意度、依从性和知识水平)和经济结局的有效性证据有限。一种多学科方法,包括医学专业人员加上药剂师、专科护士或两者,以及社区药剂师而非医院药剂师更多地参与其中,似乎代表了最有效和最现代的医疗服务提供模式。然而,需要进一步设计完善的研究,以便从定量和定性角度评估药剂师干预对心血管疾病的影响,并确定协作实践的具体影响领域。此类研究应特别关注证明对社区药剂师干预的敏感性。由于药学服务在社区环境中易于获取且分布广泛,预计在此背景下提供的干预措施将带来最大益处。

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