Perrin Raymond N
The Perrin Clinic, 11 St John St, Manchester, Greater Manchester, M3 4DW, UK.
J Am Osteopath Assoc. 2007 Jun;107(6):218-24.
The cranial rhythmic impulse is a palpable, rhythmic fluctuation believed to be synchronous with the primary respiratory mechanism. The precise physiologic mechanism of the cranial rhythmic impulse is not fully understood. Based on traditional and current views of the cranial rhythmic impulse, animal studies, and clinical findings in patients with chronic fatigue syndrome, the author argues that the cranial rhythmic impulse is the rhythm produced by a combination of cerebrospinal fluid drainage from the neuraxis (brain and spinal cord) and pulsations of central lymphatic drainage induced by the sympathetic nervous system. In addition, evidence is provided to demonstrate that a disturbed, palpable, and visible neurolymphatic process leads to chronic fatigue syndrome. This process may also explain the pathophysiologic mechanisms leading to other disease states. Finally, the author's proposed manual treatment protocol for patients with chronic fatigue syndrome is described.
颅骨节律性冲动是一种可触及的、有节律的波动，据信与主要呼吸机制同步。颅骨节律性冲动的确切生理机制尚未完全了解。基于对颅骨节律性冲动的传统和当前观点、动物研究以及慢性疲劳综合征患者的临床发现，作者认为颅骨节律性冲动是由神经轴（脑和脊髓）的脑脊液引流与交感神经系统诱导的中枢淋巴引流搏动相结合产生的节律。此外，还提供了证据表明，一种紊乱的、可触及且可见的神经淋巴过程会导致慢性疲劳综合征。这一过程也可能解释导致其他疾病状态的病理生理机制。最后，描述了作者为慢性疲劳综合征患者提出的手法治疗方案。
