• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Using model membrane-inserted hydrophobic helices to study the equilibrium between transmembrane and nontransmembrane states.

作者信息

London Erwin

出版信息

J Gen Physiol. 2007 Aug;130(2):229-32. doi: 10.1085/jgp.200709842. Epub 2007 Jul 16.

DOI:10.1085/jgp.200709842
PMID:17635963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2151635/
Abstract
摘要

相似文献

1
Using model membrane-inserted hydrophobic helices to study the equilibrium between transmembrane and nontransmembrane states.使用模型膜插入疏水螺旋来研究跨膜状态和非跨膜状态之间的平衡。
J Gen Physiol. 2007 Aug;130(2):229-32. doi: 10.1085/jgp.200709842. Epub 2007 Jul 16.
2
Titratable amino acid solvation in lipid membranes as a function of protonation state.脂质膜中可滴定氨基酸溶剂化与质子化状态的关系。
J Phys Chem B. 2009 Jan 8;113(1):245-53. doi: 10.1021/jp8048873.
3
A fluorescence method to define transmembrane alpha-helices in membrane proteins: studies with bacterial diacylglycerol kinase.一种用于确定膜蛋白中跨膜α螺旋的荧光方法：对细菌二酰基甘油激酶的研究
Biochemistry. 2007 Sep 25;46(38):10950-9. doi: 10.1021/bi7008213. Epub 2007 Aug 28.
4
Transmembrane vs. non-transmembrane hydrophobic helix topography in model and natural membranes.模型膜和天然膜中跨膜与非跨膜疏水螺旋的拓扑结构
Curr Opin Struct Biol. 2009 Aug;19(4):464-72. doi: 10.1016/j.sbi.2009.07.007. Epub 2009 Aug 7.
5
Behavior of synthetic polymers immobilized on a cell membrane.固定在细胞膜上的合成聚合物的行为。
Biomaterials. 2008 Apr;29(10):1345-55. doi: 10.1016/j.biomaterials.2007.11.048. Epub 2008 Jan 11.
6
Dependence of the energies of fusion on the intermembrane separation: optimal and constrained.融合能量对膜间距离的依赖性：最优与受限情况
J Chem Phys. 2007 Aug 21;127(7):075102. doi: 10.1063/1.2766945.
7
Temperature-dependent transmembrane insertion of the amphiphilic peptide PGLa in lipid bilayers observed by solid state 19F NMR spectroscopy.通过固态19F核磁共振光谱法观察到两亲性肽PGLa在脂质双层中与温度相关的跨膜插入。
J Am Chem Soc. 2008 Dec 10;130(49):16512-4. doi: 10.1021/ja803156d.
8
Determining the helical tilt angle of a transmembrane helix in mechanically aligned lipid bilayers using EPR spectroscopy.
J Am Chem Soc. 2007 Jun 27;129(25):7710-1. doi: 10.1021/ja071587l. Epub 2007 Jun 1.
9
Molecular binding of catechins to biomembranes: relationship to biological activity.儿茶素与生物膜的分子结合：与生物活性的关系。
J Agric Food Chem. 2009 Aug 12;57(15):6720-8. doi: 10.1021/jf900951w.
10
Deciphering membrane insertion of the diphtheria toxin T domain by specular neutron reflectometry and solid-state NMR spectroscopy.通过镜面反射中子反射测量法和固态核磁共振光谱法解析白喉毒素T结构域的膜插入过程。
J Mol Biol. 2009 Sep 4;391(5):872-83. doi: 10.1016/j.jmb.2009.06.061. Epub 2009 Jul 1.

引用本文的文献

1
Designing minimalist membrane proteins.设计极简膜蛋白。
Biochem Soc Trans. 2019 Oct 31;47(5):1233-1245. doi: 10.1042/BST20190170.

本文引用的文献

1
Membrane topography of the hydrophobic anchor sequence of poliovirus 3A and 3AB proteins and the functional effect of 3A/3AB membrane association upon RNA replication.脊髓灰质炎病毒3A和3AB蛋白疏水锚定序列的膜拓扑结构以及3A/3AB膜结合对RNA复制的功能影响。
Biochemistry. 2007 May 1;46(17):5185-99. doi: 10.1021/bi6024758. Epub 2007 Apr 7.
2
Translocation of amino acyl residues from the membrane interface to the hydrophobic core: thermodynamic model and experimental analysis using ATR-FTIR spectroscopy.氨酰基残基从膜界面到疏水核心的转位：热力学模型及使用衰减全反射傅里叶变换红外光谱的实验分析。
Mol Membr Biol. 2006 Jul-Aug;23(4):363-74. doi: 10.1080/09687860600738742.
3
An amino acid "transmembrane tendency" scale that approaches the theoretical limit to accuracy for prediction of transmembrane helices: relationship to biological hydrophobicity.一种接近跨膜螺旋预测准确性理论极限的氨基酸“跨膜倾向”量表：与生物疏水性的关系。
Protein Sci. 2006 Aug;15(8):1987-2001. doi: 10.1110/ps.062286306.
4
Peptides in lipid bilayers: the power of simple models.脂质双分子层中的肽：简单模型的力量。
Curr Opin Struct Biol. 2006 Aug;16(4):473-9. doi: 10.1016/j.sbi.2006.06.007. Epub 2006 Jul 7.
5
A synergistic effect between cholesterol and tryptophan-flanked transmembrane helices modulates membrane curvature.胆固醇与色氨酸侧翼跨膜螺旋之间的协同作用调节膜曲率。
Biochemistry. 2005 Mar 22;44(11):4526-32. doi: 10.1021/bi047937n.
6
The conformation of the pore region of the M2 proton channel depends on lipid bilayer environment.M2质子通道孔区的构象取决于脂质双分子层环境。
Protein Sci. 2005 Apr;14(4):856-61. doi: 10.1110/ps.041185805. Epub 2005 Mar 1.
7
Recognition of transmembrane helices by the endoplasmic reticulum translocon.内质网转位子对跨膜螺旋的识别。
Nature. 2005 Jan 27;433(7024):377-81. doi: 10.1038/nature03216.
8
Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylethanolamine Bilayers.基于聚亮氨酸的α-螺旋跨膜肽结构变化对其与磷脂酰乙醇胺双层膜相互作用的影响。
Biophys J. 2004 Oct;87(4):2470-82. doi: 10.1529/biophysj.104.046342.
9
Analyzing topography of membrane-inserted diphtheria toxin T domain using BODIPY-streptavidin: at low pH, helices 8 and 9 form a transmembrane hairpin but helices 5-7 form stable nonclassical inserted segments on the cis side of the bilayer.使用硼二吡咯荧光素标记的链霉亲和素分析插入膜的白喉毒素T结构域的拓扑结构：在低pH值下，螺旋8和螺旋9形成一个跨膜发夹结构，但螺旋5 - 7在双层膜的顺式侧形成稳定的非经典插入片段。
Biochemistry. 2004 Jul 20;43(28):9127-39. doi: 10.1021/bi049354j.
10
Position and ionization state of Asp in the core of membrane-inserted alpha helices control both the equilibrium between transmembrane and nontransmembrane helix topography and transmembrane helix positioning.插入膜内的α螺旋核心中天冬氨酸（Asp）的位置和电离状态控制着跨膜螺旋与非跨膜螺旋构象之间的平衡以及跨膜螺旋的定位。
Biochemistry. 2004 Jul 13;43(27):8794-806. doi: 10.1021/bi049696p.