Handoll H H, Madhok R
East Riding and Hull Health Authority, Grange Park Lane, Willerby, East Yorkshire, UK, HU10 6DT.
Cochrane Database Syst Rev. 2002(2):CD000314. doi: 10.1002/14651858.CD000314.
Fracture of the distal radius is a common clinical problem particularly in elderly white women with osteoporosis.
To determine the most appropriate conservative treatment for fractures of the distal radius in adults.
We searched the Cochrane Musculoskeletal Injuries Group specialised register (January 2002), the Cochrane Controlled Trials Register (The Cochrane Library, Issue 4, 2001), MEDLINE (1966 to January 2002), EMBASE (1988 to 2002 Week 04), CINAHL (1982 to December Week 2 2001), the National Research Register (up to Issue 4, 2001) and reference lists of articles. No language restrictions were applied.
Randomised or quasi-randomised clinical trials involving skeletally mature patients with a fracture of the distal radius, which compared commonly applied conservative interventions for fracture fixation. These included the application of an external support (plaster cast or brace) and fracture manipulation.
All trials, judged as fitting the selection criteria by both reviewers, were independently assessed by both reviewers for methodological quality. Data were extracted for anatomical, functional and clinical, including complications, outcomes. The trials were grouped into categories relating to cast position, extent and duration of immobilisation, use of braces, cast material and fracture manipulation. Although quantitative data from some trials are presented, the lack of good quality trials and trial heterogeneity inhibited pooling of results.
Two trials were newly included in this update. In all, there are 33 trials, involving a total of 3664 mainly female and older patients, meeting the inclusion criteria for this review. Comprehensive details of the individual trials are provided in tabular form, and their results, grouped as indicated above, have been presented in text and analyses tables. The poor quality and heterogeneity in terms of patient characteristics, interventions compared and outcome measurement, of the included trials meant that no meta-analyses were undertaken.
REVIEWER'S CONCLUSIONS: There remains insufficient evidence from randomised trials to determine which methods of conservative treatment are the most appropriate for the more common types of distal radial fractures in adults. Therefore, at present, practitioners applying conservative management should use an accepted technique with which they are familiar, and which is cost-effective from the perspective of their provider unit. Patient preferences and circumstances, and the risk of complications should also be considered. Further research to clarify the most appropriate conservative treatment for this common fracture is warranted but requires careful preparation with an emphasis on undertaking a systematic approach. For this, it is important to reflect on the issues raised in this review, to ascertain patient preferences, prioritise researchable questions and agree a core data set for classification of fractures and outcomes.
桡骨远端骨折是一个常见的临床问题,尤其在患有骨质疏松症的老年白人女性中更为常见。
确定成人桡骨远端骨折最合适的保守治疗方法。
我们检索了Cochrane肌肉骨骼损伤组专业注册库(2002年1月)、Cochrane对照试验注册库(Cochrane图书馆,2001年第4期)、MEDLINE(1966年至2002年1月)、EMBASE(1988年至2002年第04周)、CINAHL(1982年至2001年12月第2周)、国家研究注册库(截至2001年第4期)以及文章的参考文献列表。未设语言限制。
涉及骨骼成熟且患有桡骨远端骨折患者的随机或半随机临床试验,这些试验比较了常用于骨折固定的保守干预措施。这些措施包括应用外部支撑(石膏或支具)和骨折手法复位。
两位评审员均判定符合入选标准的所有试验,由两位评审员独立评估其方法学质量。提取有关解剖学、功能和临床方面的数据,包括并发症、结局。试验被分为与石膏位置、固定的范围和持续时间、支具的使用、石膏材料以及骨折手法复位相关的类别。尽管呈现了一些试验的定量数据,但高质量试验的缺乏以及试验的异质性阻碍了结果的合并。
本次更新新纳入了两项试验。总共有33项试验,涉及总共3664名主要为女性且年龄较大的患者,符合本综述的纳入标准。各项试验的详细信息以表格形式提供,其结果按照上述分类方式在正文和分析表中呈现。纳入试验在患者特征、比较的干预措施和结局测量方面质量较差且存在异质性,这意味着未进行荟萃分析。
随机试验中仍缺乏足够证据来确定哪种保守治疗方法最适合成人中较为常见的桡骨远端骨折类型。因此,目前采用保守治疗的从业者应使用他们熟悉且从其医疗机构角度来看具有成本效益的公认技术。还应考虑患者的偏好和情况以及并发症风险。有必要进一步开展研究以明确这种常见骨折最合适的保守治疗方法,但需要精心准备,重点是采用系统方法。为此,反思本综述中提出的问题、确定患者偏好、对可研究问题进行优先级排序以及就骨折和结局分类的核心数据集达成一致非常重要。