成人桡骨远端骨折的手术治疗干预措施。

Surgical interventions for treating distal radial fractures in adults.

作者信息

Handoll H H, Madhok R

机构信息

University of Hull, Coniston House, East Riding Campus, Willerby, East Yorkshire, UK, HU10 6NS.

出版信息

Cochrane Database Syst Rev. 2001(3):CD003209. doi: 10.1002/14651858.CD003209.

Abstract

BACKGROUND

Fracture of the distal radius is a common clinical problem, particularly in older white women with osteoporosis.

OBJECTIVES

To determine when, and if so what type of, surgical intervention is the most appropriate treatment for fractures of the distal radius in adults.

SEARCH STRATEGY

We searched the Cochrane Musculoskeletal Injuries Group's specialised register, Cochrane Controlled Trials Register (The Cochrane Library Issue 4, 2000), MEDLINE, EMBASE, CINAHL, the National Research Register (Issues 2 to 4, 2000) and bibliographies of trial reports. The full search was concluded in December 2000.

SELECTION CRITERIA

Randomised or quasi-randomised clinical trials involving skeletally mature patients with a fracture of the distal radius, which compared surgical treatment with conservative treatment, different types of surgical intervention or the duration of immobilisation after surgery. The main categories of surgical intervention were external fixation, percutaneous pinning, open reduction and internal fixation, and the insertion of bone scaffolding materials.

DATA COLLECTION AND ANALYSIS

All trials, meeting the selection criteria, were independently assessed by both reviewers for methodological quality. Data were extracted for anatomical, functional and clinical outcomes (including complications). The trials were grouped into categories relating to the main comparisons and types of surgical intervention. Despite clear heterogeneity in the characteristics of comparable trials, pooling of data was undertaken where possible and appropriate.

MAIN RESULTS

Forty four trials, examining 23 treatment comparisons, met the inclusion criteria of this review. These involved a total of 3193 mainly female and older patients with generally displaced, often comminuted and potentially or evidently unstable fractures. Half of the trials compared surgery with plaster cast immobilisation. Summarising the outcomes was hampered by the variation between the studies in participant characteristics, interventions, quality of trial methodology and reporting, and methods of outcome measurement. Surgical methods were usually associated with better anatomical appearance after fracture healing, but there was inadequate evidence to confirm that these had resulted in better functional and clinical outcomes for the patients.

REVIEWER'S CONCLUSIONS: The 44 randomised trials do not provide robust evidence for most of the decisions necessary in the management of these fractures. Although, in particular, there is some evidence to support the use of external fixation or percutaneous pinning, their precise role and methods are not established. It is also unclear whether surgical intervention of most fracture types will produce consistently better long-term outcomes. There is a need for good quality evidence for the surgical management of these fractures.

摘要

背景

桡骨远端骨折是一个常见的临床问题,在患有骨质疏松症的老年白人女性中尤为常见。

目的

确定何时以及何种类型的手术干预是成人桡骨远端骨折最恰当的治疗方法。

检索策略

我们检索了Cochrane肌肉骨骼损伤组的专业注册库、Cochrane对照试验注册库(《Cochrane图书馆》2000年第4期)、MEDLINE、EMBASE、CINAHL、国家研究注册库(2000年第2至4期)以及试验报告的参考文献。全面检索于2000年12月结束。

选择标准

涉及骨骼成熟的桡骨远端骨折患者的随机或半随机临床试验,比较手术治疗与保守治疗、不同类型的手术干预或术后固定时间。手术干预的主要类别包括外固定、经皮穿针、切开复位内固定以及骨支架材料的植入。

数据收集与分析

所有符合选择标准的试验均由两位评价者独立评估方法学质量。提取解剖学、功能和临床结局(包括并发症)的数据。试验根据主要比较和手术干预类型进行分组。尽管可比试验的特征存在明显异质性,但在可能且合适的情况下进行了数据合并。

主要结果

44项试验,涉及23种治疗比较,符合本综述的纳入标准。这些试验共纳入了3193例主要为女性和老年患者,骨折通常有移位,常为粉碎性,且潜在或明显不稳定。一半的试验比较了手术与石膏固定。研究参与者特征、干预措施、试验方法学质量和报告以及结局测量方法的差异阻碍了结局的汇总。骨折愈合后,手术方法通常与更好的解剖外观相关,但没有足够的证据证实这些方法能为患者带来更好的功能和临床结局。

评价者结论

这44项随机试验并未为这些骨折治疗中所需的大多数决策提供有力证据。虽然尤其有一些证据支持使用外固定或经皮穿针,但它们的确切作用和方法尚未明确。大多数骨折类型的手术干预是否会持续产生更好的长期结局也不清楚。这些骨折的手术治疗需要高质量的证据。

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