Groenewold Matthew R
Louisville Metro Health Department, 400 East Gray St., P.O. Box 1704, Louisville, KY 40201, USA.
Public Health Rep. 2007 Jul-Aug;122(4):521-30. doi: 10.1177/003335490712200414.
This article describes and compares the performance characteristics of two approaches to outbreak detection in the context of a coroner-based mortality surveillance system using controlled feature set simulation.
The comparative capabilities of the outbreak detection methods--the Epidemic Threshold and Cusum methods--were assessed by introducing a series of simulated signals, configured as nonoverlapping, three-day outbreaks, into historic surveillance data and assessing their respective performances. Treating each calendar day as a separate observation, sensitivity, predictive value positive, and predictive value negative were calculated for both signal detection methods at various outbreak magnitudes. Their relative performances were also assessed in terms of the overall percentage of outbreaks detected.
Both methods exhibited low sensitivity for small outbreaks and low to moderate sensitivity for larger ones. In terms of overall outbreak detection, large outbreaks were detected with moderate to high levels of reliability, while smaller ones were detected with low to moderate reliability for both methods. The Epidemic Threshold method performed significantly better than the Cusum method for overall outbreak detection.
The use of coroner data for mortality surveillance has both advantages and disadvantages, the chief advantage being the rapid availability of coroner data compared to vital statistics data, making near real-time mortality surveillance possible. Given the lack of sensitivity and limited outbreak detection reliability of the methods studied, the use of mortality surveillance for early outbreak detection appears to have limited usefulness. If it is used, it should be as an adjuvant in conjunction with other surveillance systems.
本文描述并比较了在基于验尸官的死亡率监测系统背景下,使用受控特征集模拟的两种疾病暴发检测方法的性能特征。
通过将一系列配置为不重叠的三日暴发的模拟信号引入历史监测数据,并评估其各自的性能,来评估疾病暴发检测方法(流行阈值法和累积和法)的比较能力。将每个日历日视为一个单独的观察对象,计算两种信号检测方法在不同暴发规模下的灵敏度、阳性预测值和阴性预测值。还根据检测到的暴发的总体百分比评估了它们的相对性能。
两种方法对小暴发的灵敏度都较低,对大暴发的灵敏度则为低到中等。就总体暴发检测而言,两种方法对大暴发的检测具有中等至高的可靠性,而对小暴发的检测可靠性则为低到中等。在总体暴发检测方面,流行阈值法的表现明显优于累积和法。
使用验尸官数据进行死亡率监测有其优缺点,主要优点是与生命统计数据相比,验尸官数据能快速获取,从而使近乎实时的死亡率监测成为可能。鉴于所研究方法缺乏灵敏度且疾病暴发检测可靠性有限,利用死亡率监测进行早期疾病暴发检测的作用似乎有限。如果使用,应将其作为辅助手段与其他监测系统结合使用。