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一例伪装成慢性阻塞性肺疾病的喉副球孢子菌病病例。

A case of laryngeal paracoccidioidomycosis masquerading as chronic obstructive lung disease.

作者信息

Tristano Antonio G, Díaz Lizmer

机构信息

Department of Internal Medicine, Hospital Dr. Domingo Luciani, Caracas, Venezuela.

出版信息

South Med J. 2007 Jul;100(7):709-11. doi: 10.1097/SMJ.0b013e31804b187d.

Abstract

Paracoccidioidomycosis (South American blastomycosis) is a systemic infection caused by a dimorphic fungus (Paracoccidioides brasiliensis). It is common in the rural areas of Latin America. The majority of the reported cases come from Brazil, Colombia and Venezuela. Paracoccidioidomycosis is the most important systemic mycosis of the tropical Americas and can affect any organ, causing symptomatic or asymptomatic lesions. Paracoccidioidomycosis can mimic other diseases, which must be considered in making the differential diagnosis. Patients get infected by inhaling mycelia found in the natural environment or rarely from traumatic inoculation via mucous membranes. The most common lesions frequently occur in the buccal pharynx mucosa. Others lesions occur in the larynx, adrenal glands, liver, bones, gastrointestinal tract, lungs and nervous system.

摘要

副球孢子菌病(南美芽生菌病)是一种由双相真菌(巴西副球孢子菌)引起的全身性感染。该病在拉丁美洲农村地区较为常见。报告的大多数病例来自巴西、哥伦比亚和委内瑞拉。副球孢子菌病是热带美洲最重要的全身性真菌病,可累及任何器官,导致有症状或无症状的病变。副球孢子菌病可类似其他疾病,在进行鉴别诊断时必须予以考虑。患者通过吸入自然环境中的菌丝体而感染,极少情况下通过黏膜创伤接种感染。最常见的病变常发生于颊咽黏膜。其他病变则发生于喉、肾上腺、肝脏、骨骼、胃肠道、肺和神经系统。

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