Mataix Javier, López Norberto, Haro Rosario, González Elena, Angulo Jorge, Requena Luis
Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
J Cutan Pathol. 2007 Aug;34(8):640-3. doi: 10.1111/j.1600-0560.2006.00683.x.
Dermal melanocytoses comprise a variety of congenital and acquired conditions characterized by a sparse population of intradermal dendritic, variably pigmented, spindle-shaped melanocytes. While Mongolian spot, Ota's and Ito's nevi are usually present at birth or appear around puberty; acquired dermal melanocytoses that appear in adult life are extremely rare. They include the facial lesions of acquired bilateral nevus of Ota-like macules, also named Hori's nevus, and the acquired unilateral nevus of Ota, also known as Sun's nevus. Uncommon extrafacial examples of acquired dermal melanocytoses include lesions involving upper extremities, wrist, back, lower extremities and dorsal aspects of the hands and feet. They are more prevalent among Asian women. In general, dermal melanocytoses are rare lesions in Caucasian patients and acquired variants are exceedingly uncommon. We report a rare example of acquired Ito's nevus that appeared in a Caucasian elderly woman and review the literature about acquired dermal melanocytoses.
皮肤黑素细胞增多症包括多种先天性和后天性疾病，其特征为真皮内存在少量树突状、色素沉着程度不一的梭形黑素细胞。蒙古斑、太田痣和伊藤痣通常在出生时就已存在或在青春期前后出现；而在成年期出现的后天性皮肤黑素细胞增多症极为罕见。它们包括后天性双侧太田痣样斑痣（也称为堀氏痣）的面部损害，以及后天性单侧太田痣（也称为孙氏痣）。后天性皮肤黑素细胞增多症不常见的面部以外表现包括累及上肢、手腕、背部、下肢以及手和足背的损害。它们在亚洲女性中更为常见。一般来说，皮肤黑素细胞增多症在白种人患者中是罕见的病变，后天性变种极为罕见。我们报告了一例出现在一名老年白种女性身上的罕见后天性伊藤痣病例，并对有关后天性皮肤黑素细胞增多症的文献进行了综述。
