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获得性双侧太田痣样斑伴黏膜受累:一种新的堀痣变体

Acquired Bilateral Nevus of ota-like Macules with Mucosal Involvement: A New Variant of Hori's Nevus.

作者信息

Bhat Ramesh M, Pinto Hyacinth Peter, Dandekeri Sukumar, Ambil Srinath Madapally

机构信息

Department of Dermatology, Father Muller Medical College and Hospital, Mangalore, India.

出版信息

Indian J Dermatol. 2014 May;59(3):293-6. doi: 10.4103/0019-5154.131410.

Abstract

Acquired bilateral nevus of Ota-like macules (ABNOM) or Hori's nevus, a rare form of acquired dermal melanocytoses, presents as bilateral facial blue-gray macules without ocular or mucosal involvement. This condition is mostly found in women of Asian descent and usually appears in the fourth or fifth decade of life. Pathogenesis is unknown, though few theories have been proposed. Effective treatment has been found to be achieved with pigment-specific lasers. Herein, we report a case of Hori's nevus with mucosal involvement. A 42-year-old male patient, presented to us with blue-gray discoloration on either side of his face, both eyes, and in the mouth since the age of one year. Histopathological examination showed clusters and singly dispersed pigmented melanocytes within the upper and mid-dermis regions. Special staining of melanocytes using Masson-Fontana stain was positive. Diagnosis of Hori's nevus was made by correlating clinical and histopathological findings. Patient was informed of his treatment options, but refused treatment. A similar case of Hori's nevus with mucosal involvement has not been reported so far.

摘要

获得性双侧太田痣样斑(ABNOM)或堀氏痣,是一种罕见的获得性皮肤黑素细胞增多症,表现为双侧面部蓝灰色斑,不累及眼部或黏膜。这种情况多见于亚洲裔女性,通常出现在人生的第四个或第五个十年。虽然提出了一些理论,但发病机制尚不清楚。已发现使用色素特异性激光可有效治疗。在此,我们报告一例伴有黏膜受累的堀氏痣病例。一名42岁男性患者,自1岁起面部两侧、双眼及口腔出现蓝灰色色素沉着。组织病理学检查显示在真皮上部和中部区域有成群和成单分散的色素性黑素细胞。使用Masson-Fontana染色对黑素细胞进行特殊染色呈阳性。通过临床和组织病理学检查结果的相关性做出堀氏痣的诊断。已告知患者其治疗选择,但患者拒绝治疗。目前尚未报道过类似的伴有黏膜受累的堀氏痣病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6087/4037954/553ce92d7d11/IJD-59-293-g001.jpg

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