Bessette L, Ste-Marie L-G, Jean S, Davison K S, Beaulieu M, Baranci M, Bessant J, Brown J P
Laval University, Rheumatology and Immunology Research Centre, CHUL Research Centre, Québec, QC, Canada.
Osteoporos Int. 2008 Jan;19(1):79-86. doi: 10.1007/s00198-007-0426-9. Epub 2007 Jul 20.
In women aged 50 years or more who experienced a fracture, 81% suffered a fragility fracture. Six to eight months after fragility fracture, 79% had either not been investigated for osteoporosis or prescribed anti-fracture therapy. Despite fragility fractures being common in this population osteoporosis is under-diagnosed and under-treated.
The objective of this study was to evaluate the diagnostic and treatment rates for osteoporosis six months following fragility fracture.
This prospective cohort study was set in the general community from the Province of Quebec, Canada. Women at least 50 years of age who suffered a fracture were recruited during their initial visit to the hospital and had their fracture type classified as either fragility or traumatic. Six-to-eight months after fragility fracture, women were again contacted to evaluate the diagnostic and treatment rates of osteoporosis.
Of the 2,075 women recruited over a 25 month period 1,688 (81%) sustained a fragility fracture and 387 (19%) sustained a traumatic fracture. Nine hundred and three participants with a fragility fracture were again contacted six-to-eight months after fracture. For the 739 women not on treatment on the recruitment day, only 15.4% initiated pharmacological therapy in the six-to-eight-month period following fracture and 79.0% had either not been investigated for osteoporosis or prescribed anti-fracture treatment.
The proportion of fragility fractures to total fractures is higher than previously reported. Despite the availability of diagnostic modalities, effective treatments, and adequate health care assessments, there is a substantial care gap in the management of osteoporosis.
在50岁及以上发生骨折的女性中,81%发生的是脆性骨折。脆性骨折发生6至8个月后,79%的患者未接受骨质疏松症检查或未接受抗骨折治疗。尽管脆性骨折在该人群中很常见,但骨质疏松症的诊断和治疗仍不足。
本研究的目的是评估脆性骨折6个月后骨质疏松症的诊断和治疗率。
这项前瞻性队列研究在加拿大魁北克省的普通社区进行。至少50岁且发生骨折的女性在首次就诊时被招募,并将其骨折类型分为脆性骨折或创伤性骨折。脆性骨折发生6至8个月后,再次联系这些女性以评估骨质疏松症的诊断和治疗率。
在25个月期间招募的2075名女性中,1688名(81%)发生脆性骨折,387名(19%)发生创伤性骨折。903名脆性骨折参与者在骨折后6至8个月再次被联系。对于招募当天未接受治疗的739名女性,在骨折后的6至8个月期间,只有15.4%开始接受药物治疗,79.0%的患者未接受骨质疏松症检查或未接受抗骨折治疗。
脆性骨折占总骨折的比例高于先前报道。尽管有诊断方法、有效治疗和充分的医疗保健评估,但骨质疏松症的管理仍存在很大的护理差距。