Srivastava A K, Schlessinger D
Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO 63110.
Biochimie. 1991 Jun;73(6):631-8. doi: 10.1016/0300-9084(91)90042-y.
Three trends are seen in the organization of ribosomal DNA genes during evolution: 1) gradual separation and separability of the regulation of transcription of 5S and larger subunit rRNAs; 2) retention of a transcription unit containing both large and small rRNAs; and 3) clustering of genes for both 5S and 18S-28S rDNAs, with the possible association of other 'non-rDNA' in the clusters of 18S-28S rDNA genes by the time mammals evolve.
在进化过程中，核糖体DNA基因的组织呈现出三种趋势：1）5S和较大亚基rRNA转录调控的逐渐分离和可分离性；2）保留包含大、小rRNA的转录单元；3）5S和18S - 28S rDNA基因成簇，在哺乳动物进化时，18S - 28S rDNA基因簇中可能存在其他“非rDNA”的关联。
