Kleinman Nathan L, Brook Richard A, Patel Pankaj A, Melkonian Arthur K, Brizee Truman J, Smeeding James E, Joseph-Ridge Nancy
HCMS Group, Cheyenne, WY 82001, USA.
Value Health. 2007 Jul-Aug;10(4):231-7. doi: 10.1111/j.1524-4733.2007.00173.x.
The goal of this analysis was to evaluate the impact of gout, a painful inflammatory arthritis condition, on an employed population's health-related work absence and objectively measured productivity output.
Payroll, demographic, medical, pharmaceutical, sick leave, short- and long-term disability, and workers' compensation data were collected from multiple large employers with employees widely dispersed across the United States. Data were collected during the time period of 2001 to 2004 from approximately 300,000 employees. Objective productivity output data were also available for a subset of employees (captured electronically in the form of units of work processed per person). T-tests and chi-square tests were used to compare demographic data. Two-stage multivariate regression models were used to compare annual work absence and at-work productivity between employees with and without gout, while controlling for group differences in demographics, salary, other work-related variables, and comorbidities (using the Charlson Comorbidity Index).
The annual prevalence of gout was 4.7 per 1000 employees from 2001 to 2004. Employees with gout had 4.56 more annual absence days for all categories of health-related work absence than those without gout. Objective productivity (units of work processed) results were only available for a small subsample of employees (86 with gout and 27,472 without gout). Employees with gout processed 3.51% fewer units per hour worked and 2.38% fewer units per year than employees without gout (nonsignificant at P = 0.49 and P = 0.78, respectively).
This study suggests that gout has a substantial impact on work absence and may also negatively impact productivity.
本分析的目的是评估痛风（一种疼痛性炎症性关节炎疾病）对就业人群与健康相关的工作缺勤及客观测量的生产力产出的影响。
从多家大型雇主收集了工资、人口统计学、医疗、制药、病假、短期和长期残疾以及工伤赔偿数据，这些雇主的员工广泛分布在美国各地。在2001年至2004年期间收集了约300,000名员工的数据。部分员工还可获得客观生产力产出数据（以每人处理的工作单位形式电子记录）。采用t检验和卡方检验比较人口统计学数据。使用两阶段多变量回归模型比较有痛风和无痛风员工之间的年度工作缺勤及工作时的生产力，同时控制人口统计学、薪资、其他与工作相关变量以及合并症方面的组间差异（使用查尔森合并症指数）。
2001年至2004年痛风的年患病率为每1000名员工中有4.7例。患有痛风的员工在各类与健康相关的工作缺勤方面，每年比无痛风的员工多4.56天。客观生产力（处理的工作单位）结果仅适用于一小部分员工样本（86名患有痛风，27,472名无痛风）。患有痛风的员工每工作小时处理的单位数比无痛风的员工少3.51%，每年处理的单位数少2.38%（分别在P = 0.49和P = 0.78时无统计学意义）。
本研究表明痛风对工作缺勤有重大影响，也可能对生产力产生负面影响。
