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实验动物中红细胞衰老与酶活性之间的关系。

The relationship between red cell aging and enzyme activities in experimental animals.

作者信息

Shimizu Y, Suzuki M

机构信息

Department of Veterinary Medicine, Faculty of Agriculture, Gifu University, Japan.

出版信息

Comp Biochem Physiol B. 1991;99(2):313-6. doi: 10.1016/0305-0491(91)90047-h.

DOI:10.1016/0305-0491(91)90047-h
PMID:1764909
Abstract
  1. The relationship between red cell aging and enzyme activities was studied in rabbit, guinea-pig, hamster, rats (F344/N and SD), and mice (BALB/c and DBA/2). 2. The activities of six enzymes: glucose-6-phosphate dehydrogenase (G-6-PD), 6-phosphogluconate dehydrogenase (6-PGD), hexokinase (Hx), glutamate oxaloacetate transminase (GOT), lactate dehydrogenase (LDH) and acetylcholinesterase (AChE), were measured in the red cells of different ages which were obtained either by centrifugation or experimental anaemia. 3. Hx, AChE and GOT activities were much higher in younger red cells than in older cells, hence the activities of these enzymes may be used as an indicator of age of the cells.
摘要
  1. 研究了兔、豚鼠、仓鼠、大鼠(F344/N和SD)以及小鼠(BALB/c和DBA/2)红细胞衰老与酶活性之间的关系。2. 测定了六种酶的活性:葡萄糖-6-磷酸脱氢酶(G-6-PD)、6-磷酸葡萄糖酸脱氢酶(6-PGD)、己糖激酶(Hx)、谷草转氨酶(GOT)、乳酸脱氢酶(LDH)和乙酰胆碱酯酶(AChE),这些酶活性是在通过离心或实验性贫血获得的不同年龄红细胞中测定的。3. Hx、AChE和GOT活性在较年轻红细胞中比在较老红细胞中高得多,因此这些酶的活性可用作细胞年龄的指标。

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1
The relationship between red cell aging and enzyme activities in experimental animals.实验动物中红细胞衰老与酶活性之间的关系。
Comp Biochem Physiol B. 1991;99(2):313-6. doi: 10.1016/0305-0491(91)90047-h.
2
Interstrain differences in red cell enzyme activities in mice and rats.小鼠和大鼠红细胞酶活性的品系间差异。
Comp Biochem Physiol B. 1991;100(4):687-90. doi: 10.1016/0305-0491(91)90274-h.
3
Red cell metabolism: a comparative study of some mammalian species.
Comp Biochem Physiol B. 1984;79(4):515-20. doi: 10.1016/0305-0491(84)90358-4.
4
Quantitative measurement of enzymes.酶的定量测定
Ann Clin Lab Sci (1971). 1972 Jan-Feb;2(1):57-62.
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Enzyme activities in human red blood cells of different age groups.不同年龄组人类红细胞中的酶活性。
Isr J Med Sci. 1966 May-Jun;2(3):291-6.
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The diurnal rhythm of enzymes in human red cells.人类红细胞中酶的昼夜节律。
Br J Haematol. 1976 Apr;32(4):601-7. doi: 10.1111/j.1365-2141.1976.tb00964.x.
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Comparative erythrocyte metabolism: studies using guinea pig cells.比较红细胞代谢:使用豚鼠细胞的研究。
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Blood leucocyte enzymes. II. Activities at 8-9 a.m. in cells of normal subjects, chronic lymphatic leukaemia and chronic myeloid leukaemia patients.血液白细胞酶。II. 正常受试者、慢性淋巴细胞白血病患者和慢性粒细胞白血病患者细胞在上午8 - 9点的活性。
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Red cell enzymes--III. Enzyme activities in the red blood cells of different breeds of sheep.红细胞酶——III. 不同品种绵羊红细胞中的酶活性
Comp Biochem Physiol B. 1975 Aug 15;51(4):471-3. doi: 10.1016/0305-0491(75)90041-3.
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Changes in activities of some enzymes during in vivo aging of mouse erythrocytes.小鼠红细胞体内衰老过程中某些酶活性的变化。
Proc Soc Exp Biol Med. 1968 Apr;127(4):1067-71. doi: 10.3181/00379727-127-32872.