小鼠和大鼠红细胞酶活性的品系间差异。

Interstrain differences in red cell enzyme activities in mice and rats.

Shimizu Y, Kawarada S Y, Suzuki M, Tanaka T

Department of Veterinary Medicine, Faculty of Agriculture, Gifu University, Japan.

Comp Biochem Physiol B. 1991;100(4):687-90. doi: 10.1016/0305-0491(91)90274-h.

Abstract

Interstrain differences in red blood cell enzyme activities were studied in mice (BALB/c, C57BL/6, C3H/He, DBA/2 and ddY) and rats (Donryu, F344/N, SD, Wistar and Wistar/ST), and were also compared with hamster, guinea-pig and rabbit. 2. The enzyme activities measured were: glutathione S-transferase (GST), glucose-6-phosphate dehydrogenase (G-6-PD), 6-phosphogluconate dehydrogenase (6-PGD), NADPH-diaphorase (ND), hexokinase (Hx), glutamate oxaloacetate transaminase (GOT), lactate dehydrogenase (LDH) and acetylcholinesterase (AChE). 3. There were marked variations in the activities of some red cell enzymes (e.g. GST, Hx, ND), while others (e.g. G-6-PD, 6-PGD) were much less variable both within different strains and species.

摘要

研究了小鼠（BALB/c、C57BL/6、C3H/He、DBA/2和ddY）和大鼠（Donryu、F344/N、SD、Wistar和Wistar/ST）红细胞酶活性的品系间差异，并与仓鼠、豚鼠和兔子进行了比较。2. 所测定的酶活性包括：谷胱甘肽S-转移酶（GST）、葡萄糖-6-磷酸脱氢酶（G-6-PD）、6-磷酸葡萄糖酸脱氢酶（6-PGD）、NADPH-黄递酶（ND）、己糖激酶（Hx）、谷氨酸草酰乙酸转氨酶（GOT）、乳酸脱氢酶（LDH）和乙酰胆碱酯酶（AChE）。3. 某些红细胞酶（如GST、Hx、ND）的活性存在显著差异，而其他酶（如G-6-PD、6-PGD）在不同品系和物种中的变化则小得多。