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腹腔镜下全结肠切除术和直肠结肠切除术治疗家族性腺瘤性息肉病

[Total colectomy and proctocolectomy under laparoscopic for familial adenomatous polyposis].

作者信息

Chen Kai-yun, Xiang Guo-an, Wang Han-ning, Gao Peng, Xiao Fang-lian

机构信息

Department of General Surgery, The Second People's Hospital of Guangdong Province, Guangzhou 510317, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2007 Apr 3;87(13):913-5.

Abstract

OBJECTIVE

To evaluate the efficacy and characteristics of treating familial adenomatous polyposis (FAP) by total colectomy and proctocolectomy under laparoscopy.

METHODS

The perioperative data, including surgical outcomes, safety, and recovery of 8 FAP patients, 5 males and 3 females, aged 39 (28 approximately 65), who underwent laparoscopic total colectomy and proctocolectomy were analyzed retrospectively and follow-up of 46.8 months (32 approximately 58 months) between April 2001 and January 2003 were analyzed and compared with the data of 6 patients undergoing conventional open surgery before 2001.

RESULTS

Laparoscopic total colectomy and proctocolectomy were performed successfully without severe complications on the 8 patients. The mean operation time of the laparoscopy group was 178 min, not significantly different from that of the conventional group (170 min, P>0.05). The mean intra-operative blood loss, anal exsufflation time, and hospital stay, and incision length of the laparoscopy group was 110 ml, 1.2 d, 12.5 d, and 0 cm, all significantly shorter than those of the conventional group (211 ml, 3.1 d, 17.4 d, and 22.3 cm, P<0.05 or P<0.01). Follow-up showed no local recurrence. The function of stool controlling was good 9 months after the operation.

CONCLUSION

With less trauma and pain, rapid recovery, and shorter hospital stay, laparoscopic total colectomy and proctocolectomy is feasible and safe for FAP. It must be performed by skilled and experienced surgeons.

摘要

目的

评估腹腔镜下全结肠切除术和直肠结肠切除术治疗家族性腺瘤性息肉病(FAP)的疗效及特点。

方法

回顾性分析2001年4月至2003年1月期间8例接受腹腔镜全结肠切除术和直肠结肠切除术的FAP患者(5例男性,3例女性,年龄39岁(28至65岁))的围手术期数据,包括手术结果、安全性和恢复情况,并对其进行46.8个月(32至58个月)的随访,同时与2001年前6例接受传统开放手术的患者的数据进行分析比较。

结果

8例患者均成功实施腹腔镜全结肠切除术和直肠结肠切除术,无严重并发症。腹腔镜组的平均手术时间为178分钟,与传统组(170分钟)差异无统计学意义(P>0.05)。腹腔镜组的平均术中出血量、肛门排气时间、住院时间和切口长度分别为110毫升、1.2天、12.5天和0厘米,均显著短于传统组(211毫升、3.1天、17.4天和22.3厘米,P<0.05或P<0.01)。随访显示无局部复发。术后9个月大便控制功能良好。

结论

腹腔镜全结肠切除术和直肠结肠切除术治疗FAP创伤小、疼痛轻、恢复快、住院时间短,可行且安全。该手术必须由技术熟练、经验丰富的外科医生实施。

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