Choi Hyuk, Park Il-Ho, Yoon Hu Geun, Lee Heung-Man
Medical Devices Clinical Trial Center, Guro Hospital, Department of Biomedical Engineering, Brain Korea 21 Project for Biomedical Science, College of Medicine, Seoul, Korea.
Ann Otol Rhinol Laryngol. 2011 Jun;120(6):391-6. doi: 10.1177/000348941112000608.
We compared the results of nasal sound spectral analysis (NSSA) with the results of peak nasal inspiratory flow (PNIF) testing and use of a visual analog scale in patients with allergic rhinitis with nasal obstruction.
We performed NSSA and PNIF testing on 38 patients with allergic rhinitis and 35 healthy subjects. A diagnostic decongestion test was performed on the patients (not on the control subjects). Twenty minutes after decongestant was sprayed into the nostrils, NSSA and PNIF testing were performed again.
There was a significant difference in the PNIF values and the nasal inspiratory sound intensities before and after decongestion (p < 0.001). There was a correlation between the NSSA results at the frequency range of 2 to 4 kHz and the PNIF results. The calculated cutoffs between normal and pathological values were 14.8 dB (2 to 4 kHz) for NSSA and 116 +/- 14.1 L/min for PNIF testing. No significant differences were computed between NSSA and PNIF testing in terms of sensitivity (0.71 versus 0.76) or specificity (0.74 versus 0.80).
Use of NSSA and PNIF testing together for assessment of nasal obstruction in allergic rhinitis provides clinical relevance in that it allows a fair degree of reliability. Such testing can be performed as a surrogate for rhinomanometry.
我们比较了鼻声谱分析（NSSA）的结果与峰值鼻吸气流量（PNIF）测试以及视觉模拟量表在患有鼻塞的过敏性鼻炎患者中的应用结果。
我们对38例过敏性鼻炎患者和35名健康受试者进行了NSSA和PNIF测试。对患者进行了诊断性减充血测试（对照组未进行）。在向鼻孔喷洒减充血剂20分钟后，再次进行NSSA和PNIF测试。
减充血前后PNIF值和鼻吸气声强度存在显著差异（p < 0.001）。在2至4 kHz频率范围内的NSSA结果与PNIF结果之间存在相关性。NSSA正常与病理值之间的计算临界值为14.8 dB（2至4 kHz），PNIF测试为116 +/- 14.1 L/min。在敏感性（0.71对0.76）或特异性（0.74对0.80）方面，NSSA和PNIF测试之间未计算出显著差异。
联合使用NSSA和PNIF测试评估过敏性鼻炎中的鼻塞具有临床相关性，因为它具有相当程度的可靠性。这种测试可作为鼻阻力测量的替代方法。
