Emerg Infect Dis. 2019 Dec;25(12):2264-2265. doi: 10.3201/eid2512.191022.
We assessed IgM detection in Zika patients from the 2016 outbreak in Miami-Dade County, Florida, USA. Of those with positive or equivocal IgM after 12-19 months, 87% (26/30) had IgM 6 months later. In a survival analysis, ≈76% had IgM at 25 months. Zika virus IgM persists for years, complicating serologic diagnosis.
我们评估了美国佛罗里达州迈阿密戴德县 2016 年寨卡疫情中寨卡患者的 IgM 检测情况。在 12-19 个月后 IgM 检测呈阳性或可疑的患者中,87%(26/30)在 6 个月后仍有 IgM 抗体。在生存分析中,约 76%的患者在 25 个月时仍有 IgM 抗体。寨卡病毒 IgM 持续存在多年,使血清学诊断复杂化。