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采用体外循环下心脏不停跳技术进行再次瓣膜手术。

Redo valve surgery with on-pump beating heart technique.

作者信息

Cicekcioglu F, Tutun U, Babaroglu S, Mungan U, Parlar A I, Demirtas E, Aksoyek A, Catav Z, Katircioglu S F

机构信息

Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Hospital, 06100 Sihhiye, Ankara, Turkey.

出版信息

J Cardiovasc Surg (Torino). 2007 Aug;48(4):513-8.

Abstract

AIM

Reoperations have become of increasing frequency in the last four decades. Redo surgery is more complex than primary surgery and is associated with higher mortality and morbidity. We present our immediate and mid-term results of mitral and aortic prosthetic valve replacement undertaken with beating heart technique.

METHODS

The prospective study included 26 consecutive redo valve surgery patients who underwent valve re-replacement. The operation was carried out on a beating heart using normothermic bypass without cross-clamping the aorta for mitral valve surgery and retrograde coronary sinus normothermic noncardioplegic blood perfusion during cross-clamping the aorta for aortic valve procedures.

RESULTS

Twenty-six patients (mean age 50+/-15 years) underwent reoperation with beating heart technique. Twenty (76.9%) mitral prosthetic replacements, 4 (15.4%) aortic prosthetic replacements, and 2 (7.7%) double valve replacements were achieved. Fourteen patients (53.8%) were operated for prosthetic valve dysfunction. Eighteen patients (69.2%) were in NYHA class III or IV preoperatively. Mean bypass time was 85+/-30 min. Mean duration of ventilation was 13.6+/-6 h, mean intensive unit stay was 2.8+/-6.4 days, and mean hospital stay was 8.3+/-7.2 days. Two (7.7%) patients required high dose inotropic support and in one patient (3.8%) intra-aortic balloon support was required. Pulmonary complication occurred in 1 patient (3.8%), low cardiac output in 1 patient (3.8%), and re-exploration for bleeding in 2 patients (7.7%). Operative mortality was not observed.

CONCLUSION

Normothermic on-pump beating heart valve replacement offers a safe alternative to cardioplegic arrest in high-risk group. Complication rates are low and perioperative mortality is lower than with conventional surgery. Beating heart technique has the advantage of maintaining physiologic condition of the heart throughout the procedure.

摘要

目的

在过去的四十年中,再次手术的频率越来越高。再次手术比初次手术更复杂,且与更高的死亡率和发病率相关。我们展示了采用心脏跳动技术进行二尖瓣和主动脉人工瓣膜置换的近期和中期结果。

方法

这项前瞻性研究纳入了26例连续接受再次瓣膜手术的患者,这些患者接受了瓣膜再次置换。手术在心脏跳动状态下进行,二尖瓣手术采用常温体外循环且不阻断主动脉,主动脉瓣手术在阻断主动脉期间采用逆行冠状窦常温非停跳血液灌注。

结果

26例患者(平均年龄50±15岁)采用心脏跳动技术进行了再次手术。完成了20例(76.9%)二尖瓣人工瓣膜置换、4例(15.4%)主动脉人工瓣膜置换和2例(7.7%)双瓣膜置换。14例(53.8%)患者因人工瓣膜功能障碍接受手术。18例(69.2%)患者术前为纽约心脏协会(NYHA)Ⅲ或Ⅳ级。平均体外循环时间为85±30分钟。平均通气时间为13.6±6小时,平均重症监护病房停留时间为2.8±6.4天,平均住院时间为8.3±7.2天。2例(7.7%)患者需要高剂量的正性肌力支持,1例(3.8%)患者需要主动脉内球囊支持。1例患者(3.8%)发生肺部并发症,1例患者(3.8%)出现低心排血量,2例患者(7.7%)因出血需要再次探查。未观察到手术死亡。

结论

常温体外循环心脏跳动瓣膜置换为高危组患者提供了一种安全的替代心脏停搏的方法。并发症发生率低,围手术期死亡率低于传统手术。心脏跳动技术的优点是在整个手术过程中维持心脏的生理状态。

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