Corti Marcelo, Villafañe María Florencia, Souto Liliana, Schtirbu Ricardo, Narbaitz Marina, Soler Marcela de Dios
Division of HIV/AIDS disease, F. J. Muñiz Infectious Diseases Hospital, Buenos Aires, Argentina.
Rev Soc Bras Med Trop. 2007 May-Jun;40(3):338-40. doi: 10.1590/s0037-86822007000300017.
Non-Hodgkin's lymphoma of B-cell type is the second most common neoplasm after Kaposi's sarcoma, among patients with human immunodeficiency virus infection. Most non-Hodgkin's lymphoma cases that are associated with acquired immunodeficiency syndrome involve extranodal sites, especially the digestive tract and the central nervous system. We report a case of primary lymphoma of the duodenum in a patient with AIDS. Upper gastrointestinal endoscopy revealed pseudopolypoid masses found in the second portion of the duodenum. A complete diagnostic study including histological, immunohistochemical and virological analyses showed high-grade B-cell Burkitt's lymphoma. The Epstein-Barr virus genome was detected in biopsies by immunohistochemical and in situ hybridization.
在人类免疫缺陷病毒感染患者中，B细胞型非霍奇金淋巴瘤是仅次于卡波西肉瘤的第二常见肿瘤。大多数与获得性免疫缺陷综合征相关的非霍奇金淋巴瘤病例累及结外部位，尤其是消化道和中枢神经系统。我们报告一例艾滋病患者的十二指肠原发性淋巴瘤。上消化道内镜检查显示在十二指肠第二部发现假息肉样肿物。包括组织学、免疫组织化学和病毒学分析在内的完整诊断性研究显示为高级别B细胞伯基特淋巴瘤。通过免疫组织化学和原位杂交在活检组织中检测到爱泼斯坦-巴尔病毒基因组。
