Carvalho Joana Rita, Carrilho-Ribeiro Luís, Zagalo Alexandra, Medeiros Fábio Cota, Ferreira Cristina, Velosa José
Department of Gastroenterology and Hepatology (Joana Rita Carvalho, Luís Carrilho-Ribeiro, José Velosa), Portugal.
Infectology (Alexandra Zagalo, Fábio Cota Medeiros), Portugal.
Ann Gastroenterol. 2016 Apr-Jun;29(2):230-2. doi: 10.20524/aog.2016.0021.
Gastrointestinal tract involvement in immunodeficiency-related Burkitt's lymphoma is not common and the duodenal involvement is very rare. We report the case of a 35-year-old man admitted because of abdominal pain, vomiting and weight loss. Human immunodeficiency virus infection was diagnosed and upper digestive tract endoscopy showed marked edema and hyperemia of the duodenal bulb with some violaceous areas. Immunohistochemical study of the bulbar tissue samples confirmed the diagnosis of Burkitt's lymphoma. To our knowledge, duodenal Burkitt's lymphoma affecting only the bulb has not been previously reported in the medical literature. In patients with human immunodeficiency virus infection who present with upper gastrointestinal symptoms, upper endoscopy may be diagnostic of malignancy and biopsies should be obtained from abnormal areas.
胃肠道受累于免疫缺陷相关的伯基特淋巴瘤并不常见，十二指肠受累极为罕见。我们报告一例35岁男性患者，因腹痛、呕吐和体重减轻入院。诊断为人免疫缺陷病毒感染，上消化道内镜检查显示十二指肠球部明显水肿、充血，伴有一些紫蓝色区域。球部组织样本的免疫组化研究证实了伯基特淋巴瘤的诊断。据我们所知，医学文献中此前尚未报道过仅累及球部的十二指肠伯基特淋巴瘤。对于出现上消化道症状的人免疫缺陷病毒感染患者，上消化道内镜检查可能有助于诊断恶性肿瘤，应从异常区域获取活检组织。
