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脑瘫患儿的微量营养素状况。

Micronutrient status in children with cerebral palsy.

作者信息

Hillesund Elisabet, Skranes Jon, Trygg Kerstin Ulla, Bøhmer Thomas

机构信息

Department of Pediatrics, Sorlandet Hospital, Arendal, Norway.

出版信息

Acta Paediatr. 2007 Aug;96(8):1195-8. doi: 10.1111/j.1651-2227.2007.00354.x.

Abstract

AIM

To investigate micronutrient status in a group of children with cerebral palsy (CP).

METHODS

Thirty-six children with CP, aged 1.5-17 years, completed a 4-day food diary, underwent anthropometric measurements and delivered blood for analysis of micronutrient concentrations.

RESULTS

Low intake of iron, folate, niacin, calcium, vitamin E and vitamin D was common, even among those who were receiving nutritional supplements. Laboratory tests revealed low serum concentration of folate in eight children, alpha-tocopherol in six children, ferritin in five children and pyridoxal-5-phosphate in three children. Two participants were low in zinc and one was low in selenium. Severely disabled children received nutrition supplements more frequently than those with less severe disability (71% vs.16%, p = 0.01). Tube feeding and use of nutrition supplements was reflected in higher concentrations of micronutrients in blood and serum.

CONCLUSION

Low intake of micronutrients as well as low micronutrient concentrations was common in this heterogenic group of children with CP. Children with neurological disabilities should have their nutritional status evaluated in order to ascertain sufficient intake of micronutrients.

摘要

目的

调查一组脑瘫(CP)患儿的微量营养素状况。

方法

36名年龄在1.5至17岁之间的CP患儿完成了一份为期4天的饮食日记,接受了人体测量,并采集血液用于分析微量营养素浓度。

结果

铁、叶酸、烟酸、钙、维生素E和维生素D摄入不足的情况很常见,即使在那些正在接受营养补充剂的患儿中也是如此。实验室检测显示,8名患儿血清叶酸浓度低,6名患儿α-生育酚低,5名患儿铁蛋白低,3名患儿磷酸吡哆醛低。两名参与者锌含量低,一名硒含量低。重度残疾患儿比残疾程度较轻的患儿更频繁地接受营养补充剂(71%对16%,p = 0.01)。管饲和营养补充剂的使用反映在血液和血清中微量营养素浓度较高。

结论

在这组异质性CP患儿中,微量营养素摄入不足以及微量营养素浓度低的情况很常见。患有神经残疾的儿童应评估其营养状况,以确定微量营养素的充足摄入量。

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