Schmulewitz L, Chandesris M O, Mainardi J L, Poirée S, Viard J P, Lecuit M, Mamzer-Bruneel M F, Lortholary O
Service des Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Hôpital Necker-Enfants Malades, Université Paris V, René Descartes, Paris, France.
Transpl Infect Dis. 2008 Jun;10(3):206-8. doi: 10.1111/j.1399-3062.2007.00270.x. Epub 2007 Jul 26.
Pasteurella are commensal gram-negative bacteria isolated from the oral cavity of many domesticated animals. Most human infections occur post animal bite or scratch injury resulting in local cutaneous infection; however, case reports suggest that transmission may occur via animal secretions. Pasteurella species can be associated with serious systemic infections particularly in those with underlying disease and in the immunocompromised. We present a case of invasive Pasteurella multocida sinusitis in an immunocompromised renal transplant patient most likely acquired from a pet dog through direct mucosal inoculation via licking.
巴斯德氏菌是从许多家畜口腔中分离出的共生革兰氏阴性菌。大多数人类感染发生在动物咬伤或抓伤后,导致局部皮肤感染;然而,病例报告表明,传播可能通过动物分泌物发生。巴斯德氏菌属可引起严重的全身感染,特别是在有基础疾病和免疫功能低下的人群中。我们报告一例免疫功能低下的肾移植患者发生的侵袭性多杀巴斯德氏菌鼻窦炎病例,很可能是通过宠物狗舔舐经黏膜直接接种感染的。