Eardley I, Fisher W, Rosen R C, Niederberger C, Nadel A, Sand M
Pyrah Department of Urology, St. James University Hospital, Leeds, UK.
Int J Clin Pract. 2007 Sep;61(9):1446-53. doi: 10.1111/j.1742-1241.2007.01460.x. Epub 2007 Jul 26.
To identify the prevalence of erectile dysfunction (ED) in men with diabetes, and to compare the perceptions of ED and the treatment-seeking behaviour of these men with men with ED without diabetes.
Phase I of this multinational study involved 27,839 men who were questioned about a number of men's health issues including ED, diabetes and cardiovascular conditions (i.e. hypertension, high cholesterol and angina). Epidemiological associations between these conditions were explored. Phase II involved 2912 men with self-reported ED, aged 20-75 years. Participants completed questionnaires concerning their ED, efforts to seek treatment for their ED, and potential influences that might affect treatment-seeking behaviour. Comparison of these responses was made between men with ED and diabetes and men with ED without diabetes.
There was a clear association between self-reported ED and diabetes, hypertension, angina and high cholesterol. Men with diabetes were more likely to consider their ED to be severe and permanent and to speak to a physician or a nurse about their ED, compared with men without diabetes. Sildenafil use was similar in both groups, but men with diabetes were more likely to have discontinued use, mainly because of the lack of treatment efficacy.
Men with diabetes were more likely to consider their ED to be severe and permanent, compared with men without diabetes. Furthermore, men with diabetes were more likely to discontinue sildenafil therapy, primarily because of poor efficacy. These findings suggest a need for alternative treatments for ED, especially in men with diabetes.
确定糖尿病男性勃起功能障碍(ED)的患病率,并比较这些男性与非糖尿病ED男性对ED的认知及寻求治疗的行为。
这项跨国研究的第一阶段涉及27839名男性,他们被问及一系列男性健康问题,包括ED、糖尿病和心血管疾病(即高血压、高胆固醇和心绞痛)。探讨了这些疾病之间的流行病学关联。第二阶段涉及2912名自我报告患有ED的男性,年龄在20 - 75岁之间。参与者完成了关于他们的ED、寻求ED治疗的努力以及可能影响寻求治疗行为的潜在因素的问卷。对患有ED和糖尿病的男性与患有ED但无糖尿病的男性的这些回答进行了比较。
自我报告的ED与糖尿病、高血压、心绞痛和高胆固醇之间存在明显关联。与非糖尿病男性相比,糖尿病男性更有可能认为他们的ED严重且持久,并就其ED问题咨询医生或护士。两组使用西地那非的情况相似,但糖尿病男性更有可能停药,主要原因是治疗效果不佳。
与非糖尿病男性相比,糖尿病男性更有可能认为他们的ED严重且持久。此外,糖尿病男性更有可能停止西地那非治疗,主要原因是疗效不佳。这些发现表明需要为ED提供替代治疗,尤其是在糖尿病男性中。