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肺动脉血栓切除术(已解答和未解答的问题)

Pulmonary embolectomy (answered and unanswered questions).

作者信息

Boulafendis D, Bastounis E, Panayiotopoulos Y P, Papalambros E L

机构信息

Department of Cardiovascular Surgery, Spring Branch Memorial Hospital, Houston, Texas.

出版信息

Int Angiol. 1991 Jul-Sep;10(3):187-94.

PMID:1765724
Abstract

Pulmonary embolectomy under total cardiopulmonary bypass was carried out in 16 patients with cardiogenic collapsus and hypotension not responding to vasopressors or cardiac arrest. Eleven patients (68.75%) survived and were followed up for years. Our observations are presented with special emphasis on the early and accurate diagnosis, the exact timing of the therapeutic methods, the use of the portable cardiopulmonary bypass-even in the ward, and the possibilities of decreasing the operative mortality rate in less than 30% (from 40% to 22% in our series). Despite the fact that in many countries, especially European, pulmonary artery embolectomy is no more carried out as a primary therapy for massive or submassive embolism since thrombolysis is today considered as the best therapy with a low mortality rate of 8-11%, we still believe that there is a number of patients who could benefit only from surgical intervention. Based on our own experience and that presented in the international literature, an attempt was made to discuss the existing problems, mainly diagnosis and treatment of this formidable condition, reevaluating pulmonary embolectomy.

摘要

对16例心源性休克且低血压对血管加压药无反应或心脏骤停的患者进行了体外循环下的肺动脉血栓切除术。11例患者(68.75%)存活并接受了多年随访。我们的观察结果特别强调了早期准确诊断、治疗方法的确切时机、便携式体外循环的使用——即使在病房中,以及将手术死亡率降低至30%以下(我们系列中从40%降至22%)的可能性。尽管在许多国家,尤其是欧洲,由于如今溶栓被认为是最佳治疗方法,死亡率低至8%-11%,肺动脉血栓切除术不再作为大面积或次大面积肺栓塞的主要治疗方法,但我们仍然认为有一些患者仅能从手术干预中获益。基于我们自己的经验以及国际文献中的经验,我们试图讨论现存问题,主要是这种严重疾病的诊断和治疗,重新评估肺动脉血栓切除术。

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