Makarewicz Wojciech, Kaska Lukasz, Kobiela Jarek, Stefaniak Tomasz, Krajewski Jacek, Stankiewicz Marta, Wujtewicz Magdalena A, Lachinski Andrzej J, Sledzinski Zbigniew
Department of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Poland.
Obes Surg. 2007 May;17(5):704-6. doi: 10.1007/s11695-007-9114-2.
We report a case of Wernicke's encephalopathy after sleeve gastrectomy, which had been complicated by stomach wall edema and aggravated by dietary non-compliance. Despite intense parenteral nutrition, thiamine deficiency became clinically evident. It suggests that nutritional preparations used were unable to cover the increased thiamine requirement. After intense thiamine supplementation, gradual improvement occurred during the 6 months after the diagnosis, without permanent cognitive impairment. Clinicians involved in postoperative management of bariatric surgery patients must consider Wernicke's syndrome in hyper-emetic patients, who show unclear neurological deterioration. Early diagnosis and treatment can instantly improve the patient's condition without permanent sequelae.
我们报告一例袖状胃切除术后发生韦尼克脑病的病例,该病例合并胃壁水肿,并因饮食不依从而加重。尽管进行了强化肠外营养,但硫胺素缺乏在临床上变得明显。这表明所使用的营养制剂无法满足增加的硫胺素需求。在强化补充硫胺素后,诊断后的6个月内病情逐渐改善,未出现永久性认知障碍。参与肥胖症手术患者术后管理的临床医生必须考虑在出现不明原因神经功能恶化的频繁呕吐患者中存在韦尼克综合征。早期诊断和治疗可立即改善患者病情,且无永久性后遗症。