Hernández Fernández C, Ristol Pont J, Estivill E, Batista Miranda J E, López Aramburu M A
Servicio de Urologia, Hospital Universitario Gregorio Marañón, Madrid.
Actas Urol Esp. 2007 Mar;31(3):262-9. doi: 10.1016/s0210-4806(07)73632-x.
Nocturia is the main cause of insomnia or sleep interruption in adult men, which has a negative impact on daily activities, quality of life (QoL) and quality of sleep (QoS). The assessment of nocturia and its impact on QoL and QoS in patients suffering from benign prostatic hyperplasia (BPH) has been poor in terms of clinical research, moreover there is a lack of specific methods to assess this impact.
The objectives of BPH treatment should include the improvement of patient's QoL by controlling both diurnal and nocturnal symptoms. In order to assess how nocturia affects QoL and also QoS, some specific tools, such as N-QoL questionnaire or the number of Hours of Undisturbed Sleep (HUS), have been recently developed. Therefore, it would be interesting to assess how nocturia reduction due to LUTS/BPH treatment can impact on some objective parameters such as HUS and also how nocturia reduction improves QoS and QoL. This assessment should be developed during the application of pharmacological treatments in clinical practice by means of these specific tools. With the aim of tackling nocturia as an urologic problem in patients with LUTS/BPH, as well as knowing the physiology of sleep and the effect of nocturia on the sleep and QoL, a meeting of expert urologists, that gathered about fifty specialists of all around Spain, was held in Madrid. This article presents the main ideas and concepts exposed in this meeting.
Nocturia is a symptom with a high prevalence in older patients with STUI/BPH. The PreNoc study has showed a Nocturia prevalence in Spain of 83% in patients > or =60 years old diagnosed of BPH. Nocturia is the most bothersome symptom in patients with STUI/BPH.
夜尿症是成年男性失眠或睡眠中断的主要原因，对日常活动、生活质量（QoL）和睡眠质量（QoS）有负面影响。在临床研究方面，对良性前列腺增生（BPH）患者夜尿症及其对QoL和QoS的影响评估不足，而且缺乏评估这种影响的具体方法。
BPH治疗的目标应包括通过控制日间和夜间症状来改善患者的QoL。为了评估夜尿症如何影响QoL和QoS，最近开发了一些特定工具，如N-QoL问卷或无干扰睡眠时间（HUS）。因此，评估因下尿路症状/良性前列腺增生（LUTS/BPH）治疗导致的夜尿症减少如何影响一些客观参数（如HUS），以及夜尿症减少如何改善QoS和QoL，将是很有意义的。这种评估应在临床实践中应用药物治疗时通过这些特定工具进行。为了解决LUTS/BPH患者的夜尿症这一泌尿系统问题，以及了解睡眠生理学和夜尿症对睡眠及QoL的影响，一次由来自西班牙各地约五十名专家组成的泌尿外科专家会议在马德里召开。本文介绍了本次会议提出的主要观点和概念。
夜尿症在老年STUI/BPH患者中患病率很高。PreNoc研究表明，在西班牙，年龄≥60岁且被诊断为BPH的患者中，夜尿症患病率为83%。夜尿症是STUI/BPH患者最困扰的症状。
