Oelke Matthias, Wiese Birgitt, Berges Richard
Department of Urology, OE 6240, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany,
World J Urol. 2014 Oct;32(5):1155-62. doi: 10.1007/s00345-014-1374-6. Epub 2014 Aug 8.
To evaluate the prevalence of nocturia/nocturnal voiding frequency and its impact on overall physical and mental health status in German community-dwelling men and determine which lower urinary tract symptom (LUTS) is responsible for medical consultations in the 2-year follow-up period.
A sample of German men aged 50-80 years from a community-dwelling study was chosen for re-evaluation 2 years after initial assessment. Men were clinically investigated and completed the International Prostate Symptom Score, American Urology Association-Symptom Problem Index (AUA-SPI), and the Short-Form Health Survey (SF-12).
In total, 1,562 men were eligible for analysis. Mean nocturnal voiding frequency was 2.3 for all men and increased with ageing. SF-12 data indicated that physical but not mental health status was lower than in the average population. LUTS severity reduced both physical and mental health status (p < 0.001). Clinically relevant nocturia (≥ 2 voids/night) was present in 43 % of men and reduced both physical and mental health status (p < 0.001), whereas both HRQoL scales were not significantly reduced in men without or only one nocturnal void. In multivariate regression analysis using patient-reported bother (AUA-SPI) from LUTS, only bother from nocturnal voiding was significantly associated with medical consultations in the investigated 2-year follow-up period (odds ratio 2.6; 95 % confidence interval 1.6-4.2; p < 0.001).
Our study confirmed that nocturnal voiding is highly prevalent in community-dwelling men and reduce both physical and mental health status. Bother from nocturnal voiding is the most relevant component of LUTS responsible for medical consultations in German men.
评估德国社区男性夜尿症/夜间排尿频率的患病率及其对整体身心健康状况的影响，并确定在2年随访期内导致就医的下尿路症状（LUTS）。
从一项社区居住研究中选取年龄在50 - 80岁的德国男性样本，在初次评估2年后进行重新评估。对男性进行临床检查，并完成国际前列腺症状评分、美国泌尿外科学会症状问题指数（AUA - SPI）和简短健康调查（SF - 12）。
共有1562名男性符合分析条件。所有男性的平均夜间排尿频率为2.3次，且随年龄增长而增加。SF - 12数据表明，身体健康状况而非心理健康状况低于普通人群。LUTS严重程度降低了身心健康状况（p < 0.001）。43%的男性存在临床相关夜尿症（≥ 2次/夜），这降低了身心健康状况（p < O.001），而在无夜间排尿或仅有一次夜间排尿的男性中，两个健康相关生活质量量表均未显著降低。在使用患者报告的LUTS困扰（AUA - SPI）进行的多变量回归分析中，在调查的2年随访期内，仅夜间排尿困扰与就医显著相关（优势比2.6；95%置信区间1.6 - 4.2；p < 0.001）。
我们的研究证实，夜间排尿在社区男性中非常普遍，并会降低身心健康状况。夜间排尿困扰是德国男性LUTS中导致就医的最相关因素。
