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一系列小于4毫米的黑色素瘤及其对ABCDE规则的影响。

A series of melanomas smaller than 4 mm and implications for the ABCDE rule.

作者信息

Goldsmith S M, Solomon A R

机构信息

Southwest Georgia Dermatology, 2401 Osler Court, Albany, GA 31707, USA.

出版信息

J Eur Acad Dermatol Venereol. 2007 Aug;21(7):929-34. doi: 10.1111/j.1468-3083.2006.02115.x.

Abstract

BACKGROUND

Although multiple studies have reported that a significant number of melanomas have diameters of less than or equal to 6 mm at the time of diagnosis, there has been only one series evaluating the proportion of melanomas less than 4 mm in diameter.

OBJECTIVE

The objective of this study was to determine the proportion of melanomas, in a single-practitioner, general dermatology practice, with clinical diameters less than 4 mm.

METHODS

Information regarding each new diagnosis of melanoma had been recorded during the study period of 2000-2004. Patient records and pathology reports were examined from these patients.

RESULTS

Thirteen (13.7%) of the 95 melanomas had diameters less than 4 mm at the time of presentation, including five invasive and eight in situ melanomas. The defining clinical characteristic of these lesions was intensity of pigment. Three of these 13 melanomas, including one invasive and two in situ lesions, showed features of regression.

CONCLUSIONS

The findings of this study support those authors who have suggested elimination of the 6-mm diameter criterion in the ABCDE rule. In addition, this study provides further evidence that dark colour as a diagnostic criterion for melanoma should be given more emphasis. The substitution of 'D' to represent dark instead of diameter is worthy of consideration to enhance the value of the ABCDE mnemonic.

摘要

背景

尽管多项研究报告称,大量黑色素瘤在诊断时直径小于或等于6 mm,但仅有一项系列研究评估了直径小于4 mm的黑色素瘤的比例。

目的

本研究的目的是确定在一名普通皮肤科医生的临床实践中,临床直径小于4 mm的黑色素瘤的比例。

方法

在2000 - 2004年的研究期间,记录了每次新诊断黑色素瘤的相关信息。检查了这些患者的病历和病理报告。

结果

95例黑色素瘤中有13例(13.7%)在就诊时直径小于4 mm,其中包括5例浸润性黑色素瘤和8例原位黑色素瘤。这些病变的主要临床特征是色素沉着程度。这13例黑色素瘤中有3例,包括1例浸润性病变和2例原位病变,表现出消退特征。

结论

本研究结果支持那些建议在ABCDE规则中取消6 mm直径标准的作者的观点。此外,本研究进一步证明,应更加强调深色作为黑色素瘤的诊断标准。用“D”代表深色而非直径,以增强ABCDE记忆法的价值,这值得考虑。

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