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阿拉斯加东南海岸印第安人的风湿性疾病:类风湿关节炎和系统性红斑狼疮的高患病率。

Rheumatic diseases in Alaskan Indians of the southeast coast: high prevalence of rheumatoid arthritis and systemic lupus erythematosus.

作者信息

Boyer G S, Templin D W, Lanier A P

机构信息

Internal Medicine Service, Alaska Native Medical Center, Anchorage 99501.

出版信息

J Rheumatol. 1991 Oct;18(10):1477-84.

PMID:1765971
Abstract

A review of rheumatic diseases in the southeast coastal Indians of Alaska revealed high frequencies of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Both prevalence and incidence rates of RA were significantly higher and the peak age of incidence was younger in the southeast Alaskan Indian population than in Alaskan Eskimo groups and the United States population in general. The prevalence of SLE in the Alaskan Indian population was about twice that reported for most white populations. The frequency of seronegative spondyloarthropathic disorders was similar in the Alaskan Indian and Eskimo populations. Comparable studies of the prevalence of spondyloarthropathy in general have not been carried out in white populations. The prevalence rate of ankylosing spondylitis, one of the major types of spondyloarthropathy, did not differ significantly in the SE Indians from rates in predominantly white US populations.

摘要

对阿拉斯加东南沿海印第安人的风湿性疾病进行的一项综述显示,类风湿性关节炎(RA)和系统性红斑狼疮(SLE)的发病率很高。阿拉斯加东南部印第安人群中RA的患病率和发病率均显著更高,且发病高峰年龄比阿拉斯加爱斯基摩人群体和美国总体人群更年轻。阿拉斯加印第安人群中SLE的患病率约为大多数白人人群报告患病率的两倍。血清阴性脊柱关节病性疾病在阿拉斯加印第安人和爱斯基摩人群体中的发病率相似。一般而言,尚未在白人人群中对脊柱关节病的患病率进行类似研究。脊柱关节病的主要类型之一强直性脊柱炎的患病率在东南部印第安人与美国以白人为主的人群中没有显著差异。

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