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一项针对慢性抑郁症的电话护理管理和结构化疾病自我管理小组的试点研究。

A pilot study of telephone care management and structured disease self-management groups for chronic depression.

作者信息

Ludman Evette J, Simon Gregory E, Grothaus Louis C, Luce Casey, Markley David K, Schaefer Judith

机构信息

Group Health Center for Health Studies, 1730 Minor Avenue, Seattle, WA 98101, USA.

出版信息

Psychiatr Serv. 2007 Aug;58(8):1065-72. doi: 10.1176/ps.2007.58.8.1065.

Abstract

OBJECTIVE

The authors developed, implemented, and pilot-tested intervention programs to provide effective care for chronic or recurrent depression.

METHODS

A total of 104 patients with chronic or recurrent depression were randomly assigned to one of four groups: continued usual behavioral health care, usual care plus telephone monitoring and care management by a care manager, usual care plus care management plus a peer-led chronic-disease self-management group program, or usual care plus care management plus a professionally led depression psychotherapy group. Outcomes in intent-to-treat analyses were assessed at three, six, nine, and 12 months and included treatment participation rates, Hopkins Symptom Checklist depression scale scores, major depression (Structured Clinical Interview for DSM-IV), Patient-Rated Global Improvement ratings, treatment satisfaction, and adequacy of medication.

RESULTS

Participation in care management was high in the three intervention groups. Close to 60% of participants invited to both group interventions attended at least an initial meeting, but a greater number assigned to the care management plus the professionally led group continued participation through the 12-month period. The sample was too small to reliably detect small or moderate differences in clinical outcomes, but various measures consistently favored the care management plus professionally led group.

CONCLUSIONS

It is feasible to direct additional intervention services to patients with persistent or recurring depression. A larger trial of organized self-management support for chronic depression will be necessary for a definitive evaluation of program effectiveness.

摘要

目的

作者制定、实施并进行了干预项目试点,以提供针对慢性或复发性抑郁症的有效护理。

方法

总共104名慢性或复发性抑郁症患者被随机分配到四组中的一组:继续接受常规行为健康护理、常规护理加护理经理的电话监测和护理管理、常规护理加护理管理加同伴主导的慢性病自我管理小组项目,或常规护理加护理管理加专业主导的抑郁症心理治疗小组。在意向性分析中,在3个月、6个月、9个月和12个月时评估结果,包括治疗参与率、霍普金斯症状清单抑郁量表评分、重度抑郁症(DSM-IV结构化临床访谈)、患者评定的总体改善评分、治疗满意度和药物充足性。

结果

三个干预组中护理管理的参与度较高。被邀请参加两个小组干预的参与者中,近60%至少参加了一次初始会议,但被分配到护理管理加专业主导小组的更多参与者在12个月期间持续参与。样本量太小,无法可靠地检测临床结果中的小或中度差异,但各种测量结果一致有利于护理管理加专业主导小组。

结论

为持续性或复发性抑郁症患者提供额外的干预服务是可行的。对于明确评估项目有效性而言,有必要对慢性抑郁症的有组织自我管理支持进行更大规模的试验。

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