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俄歇发射体和低射程β发射体的相对生物效应(RBE)和w(R)值,特别提及氚

RBE and w(R) values of Auger emitters and low-range beta emitters with particular reference to tritium.

作者信息

Fairlie Ian

出版信息

J Radiol Prot. 2007 Jun;27(2):157-68. doi: 10.1088/0952-4746/27/2/003. Epub 2007 May 24.

Abstract

An apparent disparity exists between RBE (relative biological effectiveness) values for low-range beta and Auger emitters, and the current value for their radiation weighting factor (w(R)). This paper presents evidence that the current w(R) value of unity for these nuclides is inconsistent with most RBE evidence and should be increased by a factor of two to three. It recommends that the ICRP should clearly state that the most appropriate RBE value for these nuclides, and not the w(R) value, should be used in specific dose calculations, retrospective dose estimations and epidemiological studies. The ICRP should also publish guidance as to the methods and data sources that could be used for these RBE values.

摘要

低能β射线和俄歇电子发射体的相对生物效应(RBE)值与它们当前的辐射权重因子(w(R))值之间存在明显差异。本文提供的证据表明,这些核素当前的w(R)值为1,这与大多数RBE证据不一致,应提高两到三倍。建议国际辐射防护委员会(ICRP)明确指出,在特定剂量计算、回顾性剂量估计和流行病学研究中,应使用这些核素最合适的RBE值,而不是w(R)值。ICRP还应发布关于可用于这些RBE值的方法和数据源的指南。

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