Michaelsen Kim Fleischer, Hoppe Camilla, Lauritzen Lotte, Mølgaard Christian
Department of Human Nutrition and LMC Centre for Advanced Food Studies, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark.
Nestle Nutr Workshop Ser Pediatr Program. 2007;60:201-219. doi: 10.1159/000106370.
There are differences between at what age industrialized countries recommend that cow's milk can be introduced to infants. Most countries recommend waiting until 12 months of age, but according to recommendations from some countries (e.g. Canada, Sweden and Denmark) cow's milk can be introduced from 9 or 10 months. The main reason for delaying introduction is to prevent iron deficiency as cow's milk is a poor iron source. In one study mainly milk intake above 500 ml/day caused iron deficiency. Cow's milk has a very low content of linoleic acid (LA), but a more favorable LA/alpha-linolenic ratio, which is likely to be the reason why red blood cell docosahexaenoic acid (DHA) levels seem to be more favorable in infants drinking cow's milk compared to infants drinking infant formula that is not supplemented with DHA. It has been suggested that cow's milk intake can affect the later risk of obesity, blood pressure and linear growth, but the evidence is not convincing. There are also considerable differences in recommendations on at what age cow's milk with reduced fat intake can be introduced. The main consideration is that low-fat milk might limit energy intake and thereby growth, but the potential effects on development of early obesity should also be considered. Recommendations about the age for introduction of cow's milk should take into consideration traditions and feeding patterns in the population, especially the intake of iron and long-chain polyunsaturated fatty acids and should also give recommendations on the volume of milk.
工业化国家在建议何时向婴儿引入牛奶的年龄方面存在差异。大多数国家建议等到12个月大,但根据一些国家(如加拿大、瑞典和丹麦)的建议,牛奶可在9或10个月大时引入。推迟引入的主要原因是预防缺铁,因为牛奶是一种较差的铁源。在一项研究中,主要是每天牛奶摄入量超过500毫升会导致缺铁。牛奶中亚油酸(LA)含量非常低,但LA/α-亚麻酸比例更有利,这可能是为什么与饮用未添加DHA的婴儿配方奶粉的婴儿相比,饮用牛奶的婴儿红细胞二十二碳六烯酸(DHA)水平似乎更有利的原因。有人提出,摄入牛奶会影响后期肥胖、血压和线性生长的风险,但证据并不确凿。在建议何时引入低脂牛奶的年龄方面也存在相当大的差异。主要考虑因素是低脂牛奶可能会限制能量摄入,从而影响生长,但也应考虑其对早期肥胖发展的潜在影响。关于引入牛奶的年龄建议应考虑人群中的传统和喂养模式,特别是铁和长链多不饱和脂肪酸的摄入量,还应就牛奶的摄入量给出建议。