Iwai Hiroshi, Nakae Kaoru, Ikeda Koshi, Ogura Manabu, Miyamoto Makoto, Omae Mariko, Kaneko Toshihiko, Yamashita Toshio
Department of Otolaryngology, Kansai Medical University, Osaka, Japan.
Otolaryngol Head Neck Surg. 2007 Aug;137(2):306-11. doi: 10.1016/j.otohns.2007.03.027.
To establish a preoperative diagnostic system and examine prognostic factors for Kimura disease.
Retrospective study.
Hospital records were reviewed for nine cases of Kimura disease treated in our department. Preoperative eosinophil counts for 74 cases with untreated malignancy in the parotid gland were also examined.
Parotid swelling with inhomogeneities and subcutaneous invasion on magnetic resonance imaging and eosinophils > 10.5 percent in Asian patients clearly indicates Kimura disease. Eosinophils > 50 percent, serum IgE levels > 10,000 IU/mL, and multifocal lesions outside salivary glands are prognostic factors suggesting disease recurrence.
A preoperative decision based on our diagnostic criteria and prognostic factors should lead to better therapeutic outcomes for Kimura disease, for which a definitive treatment policy has never been determined.
建立木村病的术前诊断系统并研究其预后因素。
回顾性研究。
回顾了我科治疗的9例木村病患者的医院记录。还检查了74例未经治疗的腮腺恶性肿瘤患者的术前嗜酸性粒细胞计数。
磁共振成像显示腮腺肿胀伴不均匀性及皮下侵犯，亚洲患者嗜酸性粒细胞>10.5%明确提示木村病。嗜酸性粒细胞>50%、血清IgE水平>10,000 IU/mL以及涎腺外多灶性病变是提示疾病复发的预后因素。
基于我们的诊断标准和预后因素做出的术前决策应能为木村病带来更好的治疗效果，而木村病尚无明确的治疗策略。
