Takeishi Meisei, Makino Yojiro, Nishioka Hiroki, Miyawaki Takeshi, Kurihara Kunihiro
From the Department of Plastic and Reconstructive Surgery, Jikei University School of Medicine, Tokyo, Japan.
J Craniofac Surg. 2007 Sep;18(5):1062-7. doi: 10.1097/scs.0b013e3180f61249.
We have encountered 11 cases of Kimura disease, comprising 10 males and 1 female. The ages at presentation ranged from 16 to 48 years, with a mean of 31.5 years. The sites of the subcutaneous masses were bilateral posterior auricular regions in two cases, frontal region in two cases, temporal region in two cases, head region in one case, parotid region in two cases, parotid and temporal regions in one case, and left earlobe in one case. The interval from onset to surgery ranged from 1 to 10 years, with a mean of 4.7 years. For diagnostic imaging, a combination of magnetic resonance imaging (MRI) and ultrasonography had a high diagnostic value. MRI depicted abnormalities at sites in contact with bone, such as posterior auricular regions, and sites with abundant soft tissue, such as parotid and cheek regions. Diffuse atrophy of subcutaneous fat was observed at the sites of the masses. On ultrasonography, the interior of lymph nodes was homogeneous and hyperechoic, whereas the periphery was hyperechoic, and blood vessels entering lymph nodes were clearly depicted. Surgery was performed in all cases. Postoperative adjuvant radiotherapy was conducted in one patient and radiotherapy and steroid therapy in one other patient. There were two relapses, and both were excised by repeated surgery. Surgical excision of the subcutaneous mass in Kimura disease has the advantages that the treatment period is short and precise histopathologic diagnosis can be obtained.
我们共遇到11例木村病患者,其中男性10例,女性1例。就诊时年龄为16至48岁,平均31.5岁。皮下肿块部位:双侧耳后区域2例,额部2例,颞部2例,头部1例,腮腺区2例,腮腺和颞部1例,左耳耳垂1例。从发病到手术的间隔时间为1至10年,平均4.7年。对于诊断性影像学检查,磁共振成像(MRI)和超声检查相结合具有较高的诊断价值。MRI显示与骨接触部位(如耳后区域)以及软组织丰富部位(如腮腺和颊部区域)的异常。在肿块部位观察到皮下脂肪弥漫性萎缩。超声检查显示,淋巴结内部均匀且高回声,而周边为高回声,进入淋巴结的血管清晰可见。所有病例均行手术治疗。1例患者术后进行了辅助放疗,另1例患者进行了放疗和类固醇治疗。有2例复发,均通过再次手术切除。木村病皮下肿块手术切除具有治疗周期短且能获得精确组织病理学诊断的优点。