Misago Noriyuki, Ohkawa Takeshi, Narisawa Yutaka
Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.
Am J Dermatopathol. 2007 Aug;29(4):404-7. doi: 10.1097/DAD.0b013e3180dd8d20.
We herein report an unusual case of apocrine carcinoma on the forehead. The lesion was formed by the anastomosis of numerous tubular structures with widespread decapitation secretion, thus demonstrating apocrine differentiation. However, we observed some unusual histopathologic features that differed from those found in typical examples of apocrine ductal carcinoma, namely: 1) a relatively well-circumscribed lesion in the dermis, and 2) nodular or solid aggregations composed of basaloid cells. We believe the present case is an apocrine ductal carcinoma, although it has a nodular appearance and basaloid cells. Otherwise, it could be a hitherto undescribed variant of apocrine carcinoma. This apocrine carcinoma on the forehead may have originated from either pluripotential cells or from apocrine glands at an unusual site.
我们在此报告一例罕见的前额大汗腺癌病例。该病变由众多管状结构吻合形成，伴有广泛的断头分泌，从而显示出大汗腺分化。然而，我们观察到一些不寻常的组织病理学特征，与典型的大汗腺导管癌不同，即：1）真皮内病变边界相对清晰；2）由基底样细胞组成的结节状或实性聚集。我们认为本病例是大汗腺导管癌，尽管它具有结节外观和基底样细胞。否则，它可能是一种迄今未描述的大汗腺癌变体。前额的这种大汗腺癌可能起源于多能细胞或异常部位的大汗腺。
