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[免疫酶细胞化学方法、单克隆抗体和凝集素在儿童淋巴组织肿瘤诊断中的应用]

[Immunoenzyme cytochemical methods, monoclonal antibodies and lectins in the diagnosis of tumors of the lymphoid tissue in children].

作者信息

Gluzman D F, Nadgornaia V A, Skliarenko L M, Abramenko I V, Sidorenko S P, Kaz'mina E V, Livshits E A, Drozdova V D

出版信息

Pediatriia. 1991(11):18-22.

PMID:1766734
Abstract

ICO, IPO and LT series monoclonal antibodies, lectins, PAP and APAAP methods were used to study blood, bone marrow and lymph node cells in children with acute lymphoblastic leukemia (ALL), non-Hodgkin's malignant lymphomas and Hodgkin's disease. The immunological phenotype of malignant lymphoid cells has been characterized and cytological variants of ALL and lymphomas of T and B cell origin have been distinguished.

摘要

采用免疫细胞化学技术(ICO、IPO和LT系列单克隆抗体、凝集素、PAP和APAAP法)对急性淋巴细胞白血病(ALL)、非霍奇金恶性淋巴瘤和霍奇金病患儿的血液、骨髓和淋巴结细胞进行研究。对恶性淋巴样细胞的免疫表型进行了鉴定,并区分了ALL以及T和B细胞源性淋巴瘤的细胞学变异型。

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